التفاصيل البيبلوغرافية
| العنوان: |
Brain-derived neurotrophic factor associated with kidney function |
| المؤلفون: |
Cheng-Yueh Hsu, Wayne Huey-Herng Sheu, I-Te Lee |
| المصدر: |
Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-10 (2023) |
| بيانات النشر: |
BMC, 2023. |
| سنة النشر: |
2023 |
| المجموعة: |
LCC:Nutritional diseases. Deficiency diseases |
| مصطلحات موضوعية: |
Brain-derived neurotrophic factor, Chronic kidney disease, Fasting, Oral glucose tolerance test, Nutritional diseases. Deficiency diseases, RC620-627 |
| الوصف: |
Abstract Background We examined the relationship between brain-derived neurotrophic factor (BDNF) and chronic kidney disease (CKD). Methods First, a cross-sectional study was conducted in 480 participants without known diabetes. An oral glucose tolerance test (OGTT) was administered after overnight fasting, and blood samples were collected at 0, 30, and 120 min. Second, a total of 3003 participants were enrolled for the case–control genetic analysis. After assigning them to a case or a control group based on age and CKD status, we investigated the association between BDNF gene variants and susceptibility to CKD. Results A higher fasting serum BDNF quartile was significantly associated with a lower prevalence of CKD (P value for trend |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1758-5996 |
| Relation: |
https://doaj.org/toc/1758-5996 |
| DOI: |
10.1186/s13098-023-00991-5 |
| URL الوصول: |
https://doaj.org/article/ac51f31d32c243de94bbcac9e3a32760 |
| رقم الانضمام: |
edsdoj.51f31d32c243de94bbcac9e3a32760 |
| قاعدة البيانات: |
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