Academic Journal

Endocrine side effects of immune checkpoint inhibitors

التفاصيل البيبلوغرافية
العنوان: Endocrine side effects of immune checkpoint inhibitors
المؤلفون: Zulma Cardona, Jeffrey A. Sosman, Sunandana Chandra, Wenyu Huang
المصدر: Frontiers in Endocrinology, Vol 14 (2023)
بيانات النشر: Frontiers Media S.A., 2023.
سنة النشر: 2023
المجموعة: LCC:Diseases of the endocrine glands. Clinical endocrinology
مصطلحات موضوعية: immune checkpoint inhibitor (ICI), endocrine side effects, hypophysitis, thyroiditis, type1 diabetes, adrenalitis, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
الوصف: Immune checkpoint inhibitors (ICIs) have increasingly been the mainstay of treatment for numerous malignancies. However, due to their association with autoimmunity, ICIs have resulted in a variety of side effects that involve multiple organs including the endocrine system. In this review article, we describe our current understanding of the autoimmune endocrinopathies as a result of the use of ICIs. We will review the epidemiology, pathophysiology, clinical presentation, diagnosis, and management of the most commonly encountered endocrinopathies, including thyroiditis, hypophysitis, Type 1 diabetes, adrenalitis, and central diabetes insipidus.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1664-2392
Relation: https://www.frontiersin.org/articles/10.3389/fendo.2023.1157805/full; https://doaj.org/toc/1664-2392
DOI: 10.3389/fendo.2023.1157805
URL الوصول: https://doaj.org/article/517e94373a8e404db7b5de93e9ff9be2
رقم الانضمام: edsdoj.517e94373a8e404db7b5de93e9ff9be2
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16642392
DOI:10.3389/fendo.2023.1157805