التفاصيل البيبلوغرافية
العنوان: |
Endocrine side effects of immune checkpoint inhibitors |
المؤلفون: |
Zulma Cardona, Jeffrey A. Sosman, Sunandana Chandra, Wenyu Huang |
المصدر: |
Frontiers in Endocrinology, Vol 14 (2023) |
بيانات النشر: |
Frontiers Media S.A., 2023. |
سنة النشر: |
2023 |
المجموعة: |
LCC:Diseases of the endocrine glands. Clinical endocrinology |
مصطلحات موضوعية: |
immune checkpoint inhibitor (ICI), endocrine side effects, hypophysitis, thyroiditis, type1 diabetes, adrenalitis, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
الوصف: |
Immune checkpoint inhibitors (ICIs) have increasingly been the mainstay of treatment for numerous malignancies. However, due to their association with autoimmunity, ICIs have resulted in a variety of side effects that involve multiple organs including the endocrine system. In this review article, we describe our current understanding of the autoimmune endocrinopathies as a result of the use of ICIs. We will review the epidemiology, pathophysiology, clinical presentation, diagnosis, and management of the most commonly encountered endocrinopathies, including thyroiditis, hypophysitis, Type 1 diabetes, adrenalitis, and central diabetes insipidus. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
1664-2392 |
Relation: |
https://www.frontiersin.org/articles/10.3389/fendo.2023.1157805/full; https://doaj.org/toc/1664-2392 |
DOI: |
10.3389/fendo.2023.1157805 |
URL الوصول: |
https://doaj.org/article/517e94373a8e404db7b5de93e9ff9be2 |
رقم الانضمام: |
edsdoj.517e94373a8e404db7b5de93e9ff9be2 |
قاعدة البيانات: |
Directory of Open Access Journals |