Endogenous origin of Pseudomonas aeruginosa infecting hospitalized patients in Ecuador

التفاصيل البيبلوغرافية
العنوان:	Endogenous origin of Pseudomonas aeruginosa infecting hospitalized patients in Ecuador
المؤلفون:	Gabriela Vasco, Mishell Achig, Belén Prado-Vivar, Maritza Páez, Franklin Espinosa, Evelyn Espinoza, Danny Quinancela, Paul Cardenas, Gabriel Trueba
المصدر:	Infection Prevention in Practice, Vol 6, Iss 1, Pp 100331- (2024)
بيانات النشر:	Elsevier, 2024.
سنة النشر:	2024
المجموعة:	LCC:Infectious and parasitic diseases LCC:Public aspects of medicine
مصطلحات موضوعية:	Pseudomonas aeruginosa, Nosocomial, Colonization, Acute infection, Whole genome sequencing, Infectious and parasitic diseases, RC109-216, Public aspects of medicine, RA1-1270
الوصف:	Summary: Recent evidence suggests that Pseudomonas aeruginosa, a bacterium that has the ability to cause deadly infections in hospitalized patients, could originate in the patient's own flora. We employed the Oxford Nanopore platform to obtain whole genome sequences (WGS) from clinical and rectal screen P. aeruginosa strains belonging to 15 patients from two hospitals. Our study found evidence that clinical and rectal isolates were clonal, with some evidence suggesting that the infecting strain was present in the patient's intestine at the time of admission, ruling out hospital acquisition. The use of WGS analysis is crucial to detect alternative sources of P. aeruginosa to develop new preventive measures against these serious infections.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2590-0889
Relation:	http://www.sciencedirect.com/science/article/pii/S2590088923000641; https://doaj.org/toc/2590-0889
DOI:	10.1016/j.infpip.2023.100331
URL الوصول:	https://doaj.org/article/e5154d3662504812809ec2d06733f0db
رقم الانضمام:	edsdoj.5154d3662504812809ec2d06733f0db
قاعدة البيانات:	Directory of Open Access Journals

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الوصف
تدمد:	25900889
DOI:	10.1016/j.infpip.2023.100331