التفاصيل البيبلوغرافية
العنوان: |
Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling |
المؤلفون: |
Lauren Brady, Michelle Kriner, Ilsa Coleman, Colm Morrissey, Martine Roudier, Lawrence D. True, Roman Gulati, Stephen R. Plymate, Zoey Zhou, Brian Birditt, Rhonda Meredith, Gary Geiss, Margaret Hoang, Joseph Beechem, Peter S. Nelson |
المصدر: |
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
بيانات النشر: |
Nature Portfolio, 2021. |
سنة النشر: |
2021 |
المجموعة: |
LCC:Science |
مصطلحات موضوعية: |
Science |
الوصف: |
The inter- and intra-tumor heterogeneity of metastatic prostate cancer (mPC) is underexplored. Here the authors use Digital Spatial Profiling to study gene and protein expression heterogeneity in 27 mPC patients, finding variation in associated pathways and potential immunotherapy targets. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-021-21615-4 |
URL الوصول: |
https://doaj.org/article/e4f2a14a1c564697b67f91b5bef0c54e |
رقم الانضمام: |
edsdoj.4f2a14a1c564697b67f91b5bef0c54e |
قاعدة البيانات: |
Directory of Open Access Journals |