التفاصيل البيبلوغرافية
| العنوان: |
Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease |
| المؤلفون: |
Caroline E. Sutton, Conor M. Finlay, Mathilde Raverdeau, James O. Early, Joseph DeCourcey, Zbigniew Zaslona, Luke A. J. O’Neill, Kingston H. G. Mills, Annie M. Curtis |
| المصدر: |
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
| بيانات النشر: |
Nature Portfolio, 2017. |
| سنة النشر: |
2017 |
| المجموعة: |
LCC:Science |
| مصطلحات موضوعية: |
Science |
| الوصف: |
Circadian controls of immune responses by the molecular clock have been reported, but the underlying mechanisms are unclear. Here the authors show that the master circadian gene, Bmal1, is essential for modulating the homeostasis of myeloid cells to control pro-inflammatory IL-17+/IFN-γ+ T cells in autoimmunity. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-017-02111-0 |
| URL الوصول: |
https://doaj.org/article/4eaabe1ffd9242d6a2d583bbb9b1dc73 |
| رقم الانضمام: |
edsdoj.4eaabe1ffd9242d6a2d583bbb9b1dc73 |
| قاعدة البيانات: |
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