التفاصيل البيبلوغرافية
| العنوان: |
Determination of antibiotic resistance pattern in different serotypes of Klebsiella pneumoniae strains isolated from hospital infections in Zarinshahr |
| المؤلفون: |
Zohreh Paknejad, Hassan Momtaz, Elahe Tajbakhsh |
| المصدر: |
بیولوژی کاربردی, Vol 8, Iss 29, Pp 21-30 (2018) |
| بيانات النشر: |
Qom Islamic Azad University, 2018. |
| سنة النشر: |
2018 |
| المجموعة: |
LCC:Biology (General) |
| مصطلحات موضوعية: |
klebsiella pneumoniae, urinary tract infections, capsule types, antibiotic resistance, zarinshahr, Biology (General), QH301-705.5 |
| الوصف: |
Background & Aim: Klebsiella pneumoniae is one of the most common gram-negative bacteria in the development of nosocomial infections, in particular urinary tract infections, which has been resistant to antibiotics in recent years. The aim of this study was to determine the pattern of antibiotic resistance in the most common capsule types of this bacterium in Zarinshahr city of Isfahan. Material and Methods: 29 strains of Klebsiella pneumoniae isolated from urinary tract infections in patients admitted to different parts of Zarinshahr Hospital in summer 2016 to summer 2017 were selected. After confirmation of phenotypic and genotype and determination of capsule types in them, antibiotic resistance pattern in isolates was determined using Kirby-bauer method, according to the CLSI standard, on the Muller Hinton Agar, 13 antibiotics were determined. Frequency of antibiotic resistance gene encoding genes including tetA, cmlA, Cat1, blaSHV, sul1, aac (3) -IV, aadA 1, qnr CITM, dfrA1, and tetB genes in isolates was determined by PCR method. Results & Conclusion: Serotype K2 with 74.51% frequency was the most commonly known capsule serotype known in isolates. All isolates had multiple antibiotic resistance and in addition to penicillin, their antibiotic resistance was the highest (10.93%) and tetracycline (44.30%) respectively. The tetA and sul1 genes with the frequency of 86.75% and 41.72% were the most common, and the two cat1 and cm1A genes with a frequency of 89.60% and 44.10% were the least common antibiotic resistance genes in Klebsiella pneumoniae strains isolated from urinary tract infections. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
Persian |
| تدمد: |
2538-3434 |
| Relation: |
https://sjoapb.qom.iau.ir/article_537376_932c929e46ce4f4cd4297e56456f9c17.pdf; https://doaj.org/toc/2538-3434 |
| URL الوصول: |
https://doaj.org/article/4d97a1d7f7364ad48492642c29f3a363 |
| رقم الانضمام: |
edsdoj.4d97a1d7f7364ad48492642c29f3a363 |
| قاعدة البيانات: |
Directory of Open Access Journals |