التفاصيل البيبلوغرافية
العنوان: |
Mucosal Cancers Arising in Potentially Malignant Lesions of the Oral Mucosa Are Marjolin Ulcers: New Insights Into Old Concepts |
المؤلفون: |
Nycolle Louise Guedes, Silvia Vanessa Lourenço, Marcello Nico |
المصدر: |
Dermatology Practical & Conceptual, Vol 14, Iss 3 (2024) |
بيانات النشر: |
Mattioli1885, 2024. |
سنة النشر: |
2024 |
المجموعة: |
LCC:Dermatology |
مصطلحات موضوعية: |
Potentially malignant lesions, premalignant lesions, oral lichen planus, Marjolin’s ulcer, squamous cell carcinoma, Dermatology, RL1-803 |
الوصف: |
Introduction: Several disparate mucocutaneous diseases present oral mucosal lesions that have been classically labeled as “pre-cancerous,” “pre-malignant,” or “potentially malignant” These include oral lichen planus, dyskeratosis congenita, tertiary syphilitic glossitis chronic graft-versus-host-disease, and oral discoid lupus erythematosus. There is much confusion in literature regarding the real malignant potential of these oral lesions in relation to the incidence of squamous cell carcinoma. Objective: We tried to unify the occurrence of squamous cell carcinoma in some oral mucosal diseases into the classic concept of Marjolin ulcer. Method: We analyzed the most relevant published evidence of the occurrence of squamous cell carcinoma (SCC) arising in oral lichen planus, dyskeratosis congenita, tertiary syphilitic glossitis chronic graft-versus-host-disease, and oral discoid lupus erythematosus, and tried to establish a logical link between them. Results: Reported cases of SCC occurring in oral lesions of these diseases seem to appear in old-standing, scarring lesions. Conclusion: Oral lichen planus, dyskeratosis congenita, tertiary syphilitic glossitis, chronic graft-versus-host-disease, and oral discoid lupus erythematosus are not “pre-malignant diseases,” their long-lasting mucosal scars are prone to the development of SCC. In this sense, this tumor can be considered a mucosal type of Marjolin ulcer. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
2160-9381 |
Relation: |
https://dpcj.org/index.php/dpc/article/view/4360; https://doaj.org/toc/2160-9381 |
DOI: |
10.5826/dpc.1403a210 |
URL الوصول: |
https://doaj.org/article/c4d3f6f790914c839705eb47ebf6193e |
رقم الانضمام: |
edsdoj.4d3f6f790914c839705eb47ebf6193e |
قاعدة البيانات: |
Directory of Open Access Journals |