Academic Journal

Mucosal Cancers Arising in Potentially Malignant Lesions of the Oral Mucosa Are Marjolin Ulcers: New Insights Into Old Concepts

التفاصيل البيبلوغرافية
العنوان: Mucosal Cancers Arising in Potentially Malignant Lesions of the Oral Mucosa Are Marjolin Ulcers: New Insights Into Old Concepts
المؤلفون: Nycolle Louise Guedes, Silvia Vanessa Lourenço, Marcello Nico
المصدر: Dermatology Practical & Conceptual, Vol 14, Iss 3 (2024)
بيانات النشر: Mattioli1885, 2024.
سنة النشر: 2024
المجموعة: LCC:Dermatology
مصطلحات موضوعية: Potentially malignant lesions, premalignant lesions, oral lichen planus, Marjolin’s ulcer, squamous cell carcinoma, Dermatology, RL1-803
الوصف: Introduction: Several disparate mucocutaneous diseases present oral mucosal lesions that have been classically labeled as “pre-cancerous,” “pre-malignant,” or “potentially malignant” These include oral lichen planus, dyskeratosis congenita, tertiary syphilitic glossitis chronic graft-versus-host-disease, and oral discoid lupus erythematosus. There is much confusion in literature regarding the real malignant potential of these oral lesions in relation to the incidence of squamous cell carcinoma. Objective: We tried to unify the occurrence of squamous cell carcinoma in some oral mucosal diseases into the classic concept of Marjolin ulcer. Method: We analyzed the most relevant published evidence of the occurrence of squamous cell carcinoma (SCC) arising in oral lichen planus, dyskeratosis congenita, tertiary syphilitic glossitis chronic graft-versus-host-disease, and oral discoid lupus erythematosus, and tried to establish a logical link between them. Results: Reported cases of SCC occurring in oral lesions of these diseases seem to appear in old-standing, scarring lesions. Conclusion: Oral lichen planus, dyskeratosis congenita, tertiary syphilitic glossitis, chronic graft-versus-host-disease, and oral discoid lupus erythematosus are not “pre-malignant diseases,” their long-lasting mucosal scars are prone to the development of SCC. In this sense, this tumor can be considered a mucosal type of Marjolin ulcer.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2160-9381
Relation: https://dpcj.org/index.php/dpc/article/view/4360; https://doaj.org/toc/2160-9381
DOI: 10.5826/dpc.1403a210
URL الوصول: https://doaj.org/article/c4d3f6f790914c839705eb47ebf6193e
رقم الانضمام: edsdoj.4d3f6f790914c839705eb47ebf6193e
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:21609381
DOI:10.5826/dpc.1403a210