التفاصيل البيبلوغرافية
| العنوان: |
Long-Term Outcomes of Children and Adolescents With Postural Tachycardia Syndrome After Conventional Treatment |
| المؤلفون: |
Chunyan Tao, Wenxin Lu, Jing Lin, Hongxia Li, Xueying Li, Chaoshu Tang, Junbao Du, Hongfang Jin |
| المصدر: |
Frontiers in Pediatrics, Vol 7 (2019) |
| بيانات النشر: |
Frontiers Media S.A., 2019. |
| سنة النشر: |
2019 |
| المجموعة: |
LCC:Pediatrics |
| مصطلحات موضوعية: |
postural tachycardia syndrome, conventional interventions, long-term outcomes, children, adolescents, Pediatrics, RJ1-570 |
| الوصف: |
Objectives: To explore the long-term outcomes of children and adolescents with postural tachycardia syndrome receiving conventional interventions.Materials and Methods: A total of 121 patients were recruited, but 6 (5.0%) of them were lost at follow-up. The detailed clinical data were collected, and the reoccurrence and frequency of orthostatic intolerance symptoms were evaluated with a mean followed-up period of 18.7 months (range, 14–74 months). The Kaplan-Meier curve was used to show the cumulative symptom-free rate of patients over time. Factors influencing the long-term outcomes were examined using the Cox's proportional hazards models.Results: The cumulative symptom-free rate was gradually increased over time. It was 48.4% at the 1-year follow-up and increased to 85.6% at the 6-year follow-up. The duration of symptoms before treatment and the maximum upright heart rate in standing-up test were identified as independent indicators for the long-term outcomes. Each 1-month prolongation in the duration of symptoms before treatment was associated with a 1.2% decrease in the cumulative symptom-free rate. However, each 1-bpm increase in the maximum upright heart rate in standing-up test was associated with a 2.1% increase in the cumulative symptom-free rate.Conclusions: The long-term outcomes of postural tachycardia syndrome patients who received conventional interventions are benign and the cumulative symptom-free rate was gradually increased over time. The prolonged duration of symptoms before treatment and the reduced maximum upright heart rate in standing-up test are the independent risk indicators. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2296-2360 |
| Relation: |
https://www.frontiersin.org/article/10.3389/fped.2019.00261/full; https://doaj.org/toc/2296-2360 |
| DOI: |
10.3389/fped.2019.00261 |
| URL الوصول: |
https://doaj.org/article/dad4cc1df6c548e5b527622ec5432e4d |
| رقم الانضمام: |
edsdoj.4cc1df6c548e5b527622ec5432e4d |
| قاعدة البيانات: |
Directory of Open Access Journals |
Full Text Finder