Academic Journal
Impact of monocarbonyl analogs of curcumin (MACs) C66 and B2BrBC on the expression of diabetes-associated genes in streptozotocin-treated rat pancreatic RIN-m cells—Quantitative RT-PCR array data
| العنوان: | Impact of monocarbonyl analogs of curcumin (MACs) C66 and B2BrBC on the expression of diabetes-associated genes in streptozotocin-treated rat pancreatic RIN-m cells—Quantitative RT-PCR array data |
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| المؤلفون: | Radoslav Stojchevski, Sara Velichkovikj, Jane Bogdanov, Nikola Hadzi-Petrushev, Mitko Mladenov, Leonid Poretsky, Dimiter Avtanski |
| المصدر: | Data in Brief, Vol 57, Iss , Pp 110952- (2024) |
| بيانات النشر: | Elsevier, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Computer applications to medicine. Medical informatics LCC:Science (General) |
| مصطلحات موضوعية: | Monocarbonyl analogs of curcumin (MACs), Streptozotocin (STZ), Pancreatic β-cells, Gene expression, Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390 |
| الوصف: | This paper presents a dataset obtained from an RT2-qPCR array analysis of rat pancreatic RIN-m cells treated with two monocarbonyl analogs of curcumin (MACs), C66 and B2BrBC in the presence or absence of streptozotocin (STZ). The array quantified the expression of 84 genes associated with the onset, development, and progression of diabetes. This dataset provides information on the gene expression profiles of pancreatic cells modulated by two specific MACs in a diabetic context. The data can serve as a foundation for developing new hypotheses, designing follow-up experiments, and identifying novel targets for treatment. It can be used to investigate further the molecular mechanisms underlying the therapeutic effects of these MACs and in comparative studies using other experimental antidiabetic compounds. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2352-3409 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2352340924009144; https://doaj.org/toc/2352-3409 |
| DOI: | 10.1016/j.dib.2024.110952 |
| URL الوصول: | https://doaj.org/article/a4be3db87d0e416ab86bd6a0c0e47547 |
| رقم الانضمام: | edsdoj.4be3db87d0e416ab86bd6a0c0e47547 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23523409 |
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| DOI: | 10.1016/j.dib.2024.110952 |