Academic Journal
Photoacoustic imaging of squirrel monkey cortical and subcortical brain regions during peripheral electrical stimulation
| العنوان: | Photoacoustic imaging of squirrel monkey cortical and subcortical brain regions during peripheral electrical stimulation |
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| المؤلفون: | Kai-Wei Chang, Yunhao Zhu, Heather M. Hudson, Scott Barbay, David J. Guggenmos, Randolph J. Nudo, Xinmai Yang, Xueding Wang |
| المصدر: | Photoacoustics, Vol 25, Iss , Pp 100326- (2022) |
| بيانات النشر: | Elsevier, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Physics LCC:Acoustics. Sound LCC:Optics. Light |
| مصطلحات موضوعية: | Non-human primate, Photoacoustic imaging, Photoacoustic computed tomography, Photoacoustic microscopy, Peripheral electrical stimulation, Physics, QC1-999, Acoustics. Sound, QC221-246, Optics. Light, QC350-467 |
| الوصف: | The investigation of neuronal activity in non-human primate models is of critical importance due to their genetic similarity to human brains. In this study, we tested the feasibility of using photoacoustic imaging for the detection of cortical and subcortical responses due to peripheral electrical stimulation in a squirrel monkey model. Photoacoustic computed tomography and photoacoustic microscopy were applied on squirrel monkeys for real-time deep subcortical imaging and optical-resolution cortical imaging, respectively. The electrically evoked hemodynamic changes in primary somatosensory cortex, premotor cortices, primary motor cortex, and underlying subcortical areas were measured. Hemodynamic responses were observed in both cortical and subcortical brain areas at the cortices during external stimulation, demonstrating the feasibility of photoacoustic technique for functional imaging of non-human primate brain. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2213-5979 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2213597921000847; https://doaj.org/toc/2213-5979 |
| DOI: | 10.1016/j.pacs.2021.100326 |
| URL الوصول: | https://doaj.org/article/4be0d06896004b44b5903e6e426574e9 |
| رقم الانضمام: | edsdoj.4be0d06896004b44b5903e6e426574e9 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22135979 |
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| DOI: | 10.1016/j.pacs.2021.100326 |