Academic Journal

The role of inflammation in central serous chorioretinopathy: From mechanisms to therapeutic prospects

التفاصيل البيبلوغرافية
العنوان: The role of inflammation in central serous chorioretinopathy: From mechanisms to therapeutic prospects
المؤلفون: Xiao Shen, Fanhua Kong, Jing Wen, Xiao Wang, Chunlian Huang
المصدر: Frontiers in Pharmacology, Vol 15 (2024)
بيانات النشر: Frontiers Media S.A., 2024.
سنة النشر: 2024
المجموعة: LCC:Therapeutics. Pharmacology
مصطلحات موضوعية: central serous chorioretinopathy, inflammation, cytokines, chemokines, therapy, Therapeutics. Pharmacology, RM1-950
الوصف: Central serous chorioretinopathy (CSC) is a leading cause of permanent vision loss, ranking fourth among macular diseases, trailing only age-related macular degeneration, diabetic retinopathy, and retinal vein obstruction. While mounting evidence implicates inflammation as a pivotal factor in the onset and advancement of CSC, the specific pathophysiological process and molecular mechanisms underlying inflammation remain incompletely understood. A complex network of cytokines, chemokines, and adhesion molecules interplay to trigger inflammatory and pathological cascades, highlighting the need for a comprehensive comprehension of the inflammation-related mechanisms behind CSC progression. In this piece, we examine the existing comprehension of CSC’s pathology and pathogenesis. Additionally, we present an overview of the mechanisms underlying the onset and progression of CSC inflammation, followed by a thorough analysis and discussion of the potential of targeted inflammatory intervention for both preventing and treating CSC.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1663-9812
Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1200492/full; https://doaj.org/toc/1663-9812
DOI: 10.3389/fphar.2024.1200492
URL الوصول: https://doaj.org/article/e4bd3bcdb96e4cc4abc9a6f852289990
رقم الانضمام: edsdoj.4bd3bcdb96e4cc4abc9a6f852289990
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16639812
DOI:10.3389/fphar.2024.1200492