Academic Journal
AePUb promoter length modulates gene expression in Aedes aegypti
العنوان: | AePUb promoter length modulates gene expression in Aedes aegypti |
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المؤلفون: | Michelle A. E. Anderson, Philip T. Leftwich, Ray Wilson, Leonela Z. Carabajal Paladino, Sanjay Basu, Sara Rooney, Zach N. Adelman, Luke Alphey |
المصدر: | Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023) |
بيانات النشر: | Nature Portfolio, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Medicine LCC:Science |
مصطلحات موضوعية: | Medicine, Science |
الوصف: | Abstract Molecular tools for modulating transgene expression in Aedes aegypti are few. Here we demonstrate that adjustments to the AePUb promoter length can alter expression levels of two reporter proteins in Ae. aegypti cell culture and in mosquitoes. This provides a simple means for increasing or decreasing expression of a gene of interest and easy translation from cells to whole insects. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2045-2322 41570014 |
Relation: | https://doaj.org/toc/2045-2322 |
DOI: | 10.1038/s41598-023-47777-3 |
URL الوصول: | https://doaj.org/article/e4baf41570014ae0bae6694211dc1f2d |
رقم الانضمام: | edsdoj.4baf41570014ae0bae6694211dc1f2d |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20452322 41570014 |
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DOI: | 10.1038/s41598-023-47777-3 |