التفاصيل البيبلوغرافية
| العنوان: |
Crohn’s Disease: Basic Characteristics of the Disease, Diagnostic Methods, the Role of Biomarkers, and Analysis of Metalloproteinases: A Review |
| المؤلفون: |
Grzegorz Pasternak, Grzegorz Chrzanowski, David Aebisher, Angelika Myśliwiec, Klaudia Dynarowicz, Dorota Bartusik-Aebisher, Barbara Sosna, Grzegorz Cieślar, Aleksandra Kawczyk-Krupka, Rafał Filip |
| المصدر: |
Life, Vol 13, Iss 10, p 2062 (2023) |
| بيانات النشر: |
MDPI AG, 2023. |
| سنة النشر: |
2023 |
| المجموعة: |
LCC:Science |
| مصطلحات موضوعية: |
Crohn’s disease, characteristics, diagnostics, metalloproteinases, Science |
| الوصف: |
Crohn’s disease is a chronic inflammatory bowel disease that affects the ileum and/or large intestine. At the same time, it can also affect any other part of the human body, i.e., from the mouth to the anus. In Crohn’s disease, the physiology and functioning of the epithelial barrier are inhibited due to the correlation of various factors, such as the environment, genetic susceptibility or intestinal microbiota. The symptoms are very troublesome and cause a significant reduction in quality of life, sometimes occurring with paralyzing permanent damage to the digestive tract, requiring enteral or parenteral nutrition throughout life. In order to make a proper and accurate diagnosis, an appropriately selected diagnostic path in a given clinical entity is necessary. Standard diagnostic methods are: laboratory examination, histopathological examination, endoscopic examination, X-ray, computed tomography, ultrasound examination and magnetic resonance imaging. Medical biology and the analysis of metalloproteinases have also proved helpful in diagnosing changes occurring as a result of Crohn’s disease. Here we provide a thorough review of the latest reports on Crohn’s disease and its genetic conditions, symptoms, morphology, diagnosis (including the analysis of Crohn’s disease biomarkers, i.e., metalloproteinases) and treatment. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2075-1729 |
| Relation: |
https://www.mdpi.com/2075-1729/13/10/2062; https://doaj.org/toc/2075-1729 |
| DOI: |
10.3390/life13102062 |
| URL الوصول: |
https://doaj.org/article/d4b71e69523b40eab34e4a21576a5352 |
| رقم الانضمام: |
edsdoj.4b71e69523b40eab34e4a21576a5352 |
| قاعدة البيانات: |
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