Academic Journal
Effectiveness of the Topical Application of 4% Chlorhexidine on Umbilical Cord Bacterial Colonization – A Non-Randomized Control Study
| العنوان: | Effectiveness of the Topical Application of 4% Chlorhexidine on Umbilical Cord Bacterial Colonization – A Non-Randomized Control Study |
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| المؤلفون: | B.P. Prasanna, Kiran Baliga, K. Vishwas Saralaya, P. Anupama Nayak, S.R. Ravikiran |
| المصدر: | Journal of Pure and Applied Microbiology, Vol 17, Iss 4, Pp 2188-2193 (2023) |
| بيانات النشر: | Journal of Pure and Applied Microbiology, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Microbiology |
| مصطلحات موضوعية: | 4% chlorhexidine, cord care, colonization, Microbiology, QR1-502 |
| الوصف: | Newborns have the highest risk of death in the first 4 weeks of their life. Umbilical cord of a child is an important site for microorganism colonization and also forms a portal of entry for invasive pathogens. This study focuses on the bacterial colonization with 2 separate cord care regimens: dry cord and 4% chlorhexidine care group. This is a randomized control time-bound study conducted at a tertiary health care centre in Mangalore. A total of 144 newborns fulfilling the inclusion criteria were included and then divided randomly into two groups: dry cord care and 4% chlorhexidine. Two swabs were collected, baseline swab (swab 1) within 3 hours of birth and second swab (swab 2) at 120± 10 hours of birth and these samples were cultured for gram negative and positive organisms. Results were evaluvated with Chi-Square test. Out of 144 samples, in 115 showed no growth at the baseline and only 29 showed growth. In the dry cord care group, 38.9% showed growth of microorganism in comparison with chlorhexidine group which was 1.4% in swab 1 (baseline) and in swab 2, 87.5% in dry cord care group and 18.1% in chlrohexidine group in swab 2 respectively. It was observed that methicilin susceptible Staphylococcus aureus (MSSA) and methicillin resistant Staphylococcus aureus (MRSA) were the most common microorganisms isolated with others being Pseudomonas species, coagulase-negative Staphylococci (CoNS), Enterobacter species and Citrobacter species. Use of 4% chlorhexidine is effective in reducing colonization of bacteria and infection in comparison with dry cord care method. Therefore, decontamination of the umbilical cord with 4% of chlorhexidine should be recommended in a newborn child. However, both cord care methods did not lead to any infections. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0973-7510 2581-690X |
| Relation: | https://microbiologyjournal.org/effectiveness-of-the-topical-application-of-4-chlorhexidine-on-umbilical-cord-bacterial-colonization-a-non-randomized-control-study/; https://doaj.org/toc/0973-7510; https://doaj.org/toc/2581-690X |
| DOI: | 10.22207/JPAM.17.4.15 |
| URL الوصول: | https://doaj.org/article/4a6d30ad314b4d48814144277656ea2f |
| رقم الانضمام: | edsdoj.4a6d30ad314b4d48814144277656ea2f |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 09737510 2581690X |
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| DOI: | 10.22207/JPAM.17.4.15 |