Academic Journal
Histone modifications in neurodifferentiation of embryonic stem cells
| العنوان: | Histone modifications in neurodifferentiation of embryonic stem cells |
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| المؤلفون: | Min Huang, Xiaoxiao Xiao, Guanxu Ji, Qiang Wu |
| المصدر: | Heliyon, Vol 8, Iss 1, Pp e08664- (2022) |
| بيانات النشر: | Elsevier, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Science (General) LCC:Social sciences (General) |
| مصطلحات موضوعية: | Histone modifications, Chromatin landscape, Embryonic stem cells, Neurodifferentiation, Science (General), Q1-390, Social sciences (General), H1-99 |
| الوصف: | Post-translational modifications of histone proteins regulate a long cascade of downstream cellular activities, including transcription and replication. Cellular lineage differentiation involves large-scale intracellular signaling and extracellular context. In particular, histone modifications play instructive and programmatic roles in central nervous system development. Deciphering functions of histone could offer feasible molecular strategies for neural diseases caused by histone modifications. Here, we review recent advances of in vitro and in vivo studies on histone modifications in neural differentiation. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2405-8440 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2405844021027675; https://doaj.org/toc/2405-8440 |
| DOI: | 10.1016/j.heliyon.2021.e08664 |
| URL الوصول: | https://doaj.org/article/499b1abeb678455898c0e9f9ee9271c3 |
| رقم الانضمام: | edsdoj.499b1abeb678455898c0e9f9ee9271c3 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 24058440 |
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| DOI: | 10.1016/j.heliyon.2021.e08664 |