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How does the GINA definition of control correlate with quality of life and sputum cellularity?

التفاصيل البيبلوغرافية
العنوان: How does the GINA definition of control correlate with quality of life and sputum cellularity?
المؤلفون: Marcia Margaret Menezes Pizzichini, Cristiane Cinara Rocha, Michelle Gonçalves de Souza Tavares, Leila John Marques Steidle, Rosemeri Maureci da Silva, Felipe dal Pizzol, Peter G. Gibson, Emilio Pizzichini
المصدر: ERJ Open Research, Vol 5, Iss 1 (2019)
بيانات النشر: European Respiratory Society, 2019.
سنة النشر: 2019
المجموعة: LCC:Medicine
مصطلحات موضوعية: Medicine
الوصف: Since 2014, the Global Initiative for Asthma (GINA) has stated that asthma control should be measured using four questions concerning diurnal and nocturnal symptoms, activity limitation, and rescue medication use. We assessed how asthma control by this definition correlates with airway inflammation and quality of life. 113 asthmatic subjects consecutively recruited from their routine clinical appointment underwent spirometry, sputum induction and answered the Standardised Asthma Quality of Life Questionnaire (AQLQ(S)) during a single visit. 43 (38.1%), 37 (32.7%) and 33 (29.2%) subjects had controlled asthma, partly controlled asthma and uncontrolled asthma, respectively. The majority of subjects with controlled asthma (67.4%) had paucigranulocytic sputum. Eosinophilic sputum was present in all levels of asthma control. Although most subjects with controlled asthma (58.1%) achieved an AQLQ(S) score ≥6 (minimal or no impairment), the remaining patients (41.9%) had moderate/some impairment (AQLQ(S) score
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2312-0541
23120541
Relation: http://openres.ersjournals.com/content/5/1/00146-2018.full; https://doaj.org/toc/2312-0541
DOI: 10.1183/23120541.00146-2018
URL الوصول: https://doaj.org/article/49112da94e74425398177dc152d62c32
رقم الانضمام: edsdoj.49112da94e74425398177dc152d62c32
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:23120541
DOI:10.1183/23120541.00146-2018