التفاصيل البيبلوغرافية
| العنوان: |
Dengue in Pune city, India (2017–2019): a comprehensive analysis |
| المؤلفون: |
Vidya Arankalle, Shubham Shrivastava, Ruta Kulkarni, Rahul Patil, Divya Tiraki, Sanjay Mankar, Rohini Mahesh Taru, Raj Lavange, Arundhati Diwan, Sanjay Lalwani, AkhileshChandra Mishra |
| المصدر: |
Frontiers in Public Health, Vol 12 (2024) |
| بيانات النشر: |
Frontiers Media S.A., 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Public aspects of medicine |
| مصطلحات موضوعية: |
dengue, symptoms, disease category, primary dengue, secondary dengue, India, Public aspects of medicine, RA1-1270 |
| الوصف: |
ObjectivesTo understand the dynamics of dengue disease with special reference to (1) age (2) primary/secondary infections (3) serostatus and (4) serotypes examined during three consecutive years.MethodsDuring 3 dengue seasons (2017–19), NS1/IgM ELISAs were used for dengue diagnosis in one of the 15 administrative wards of Pune City, India. Predefined symptoms were recorded at the time of diagnosis/hospitalization. IgG-capture ELISA (Panbio) was used to differentiate primary/secondary infections. DENV serotypes were determined for 260 viral RNA-positive patients.ResultsDuring the 3 years, 3,014/6,786 (44.4%, 41.4–49.9%) suspected cases were diagnosed as dengue. Use of either NS1 or IgM would have missed 25.5% or 43% of the confirmed dengue cases, respectively. Notably, a higher proportion of secondary dengue cases remained mild while a substantial proportion of primary infections developed warning signs. The symptoms among Dengue/non-dengue patients and primary/secondary infections varied and influenced by age and serostatus. The number and proportion of dengue serotypes varied yearly. A remarkable decline in dengue cases was observed during the COVID-19 pandemic years.ConclusionA substantial proportion of primary and secondary dengue patients progress to warning signs/severity or mild infection respectively, underscoring the possible role of non-ADE mechanisms in causing severe dengue that requires hospitalization. Both NS1 and IgM should be used for efficient diagnosis. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2296-2565 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fpubh.2024.1354510/full; https://doaj.org/toc/2296-2565 |
| DOI: |
10.3389/fpubh.2024.1354510 |
| URL الوصول: |
https://doaj.org/article/46c23246f947403dbf64ee31b446d70b |
| رقم الانضمام: |
edsdoj.46c23246f947403dbf64ee31b446d70b |
| قاعدة البيانات: |
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