Academic Journal

Olivocochlear Efferent Function: Issues regarding methods and the interpretation of results

التفاصيل البيبلوغرافية
العنوان: Olivocochlear Efferent Function: Issues regarding methods and the interpretation of results
المؤلفون: John J. Guinan
المصدر: Frontiers in Systems Neuroscience, Vol 8 (2014)
بيانات النشر: Frontiers Media S.A., 2014.
سنة النشر: 2014
المجموعة: LCC:Neurosciences. Biological psychiatry. Neuropsychiatry
مصطلحات موضوعية: Attention, task difficulty, auditory psychophysics, MOC, olivocochlear efferents, medial olivocochlear, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
الوصف: As studies of the olivocochlear (OC) efferent system have matured, issues have been identified that need to be taken into account in the design of new studies and in the interpretation of existing work. The need for high signal-to-noise ratios (SNRs), multiple alternations of conditions, and avoiding middle-ear-muscle activation have been previously highlighted. Less well-known issues include: Contralateral medial OC (MOC) effects may not be good proxies for ipsilateral MOC effects; MOC-induced changes in otoacoustic emissions (OAEs) may not accurately show MOC-induced changes in auditory-nerve responses; Measuring OAE differences from before to after psychophysical trials yields the transient OAE change but not tonic MOC activation; Tonic MOC activation may be measurable by several techniques including by OAE differences in trials in which the subject’s judgment was correct versus trials that were incorrect; SNRs can be preserved by Bootstrap statistical tests; Differences in task difficulty may outweigh differences in subject attention; Lateral efferent effects are little understood and may be tied to MOC effects; To assess whether MOC strength predicts protection from acoustic trauma, prospective tests in humans are needed.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1662-5137
Relation: http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00142/full; https://doaj.org/toc/1662-5137
DOI: 10.3389/fnsys.2014.00142
URL الوصول: https://doaj.org/article/4535e42aea8e400591083668f6d5c722
رقم الانضمام: edsdoj.4535e42aea8e400591083668f6d5c722
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16625137
DOI:10.3389/fnsys.2014.00142