Academic Journal
Reduced neural sensitivity to rapid individual face discrimination in autism spectrum disorder
| العنوان: | Reduced neural sensitivity to rapid individual face discrimination in autism spectrum disorder |
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| المؤلفون: | Sofie Vettori, Milena Dzhelyova, Stephanie Van der Donck, Corentin Jacques, Jean Steyaert, Bruno Rossion, Bart Boets |
| المصدر: | NeuroImage: Clinical, Vol 21, Iss , Pp - (2019) |
| بيانات النشر: | Elsevier, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Computer applications to medicine. Medical informatics LCC:Neurology. Diseases of the nervous system |
| مصطلحات موضوعية: | Computer applications to medicine. Medical informatics, R858-859.7, Neurology. Diseases of the nervous system, RC346-429 |
| الوصف: | Background: Individuals with autism spectrum disorder (ASD) are characterized by impairments in social communication and interaction. Although difficulties at processing social signals from the face in ASD have been observed and emphasized for many years, there is a lot of inconsistency across both behavioral and neural studies. Methods: We recorded scalp electroencephalography (EEG) in 23 8-to-12 year old boys with ASD and 23 matched typically developing boys using a fast periodic visual stimulation (FPVS) paradigm, providing objective (i.e., frequency-tagged), fast (i.e., few minutes) and highly sensitive measures of rapid face categorization, without requiring any explicit face processing task. We tested both the sensitivity to rapidly (i.e., at a glance) categorize faces among other objects and to individuate unfamiliar faces. Outcomes: While general neural synchronization to the visual stimulation and neural responses indexing generic face categorization were undistinguishable between children with ASD and typically developing controls, neural responses indexing individual face discrimination over the occipito-temporal cortex were substantially reduced in the individuals with ASD. This difference vanished when faces were presented upside-down, due to the lack of significant face inversion effect in ASD. Interpretation: These data provide original evidence for a selective high-level impairment in individual face discrimination in ASD in an implicit task. The objective and rapid assessment of this function opens new perspectives for ASD diagnosis in clinical settings. Keywords: Autism, EEG, Face processing |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2213-1582 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2213158218303590; https://doaj.org/toc/2213-1582 |
| DOI: | 10.1016/j.nicl.2018.101613 |
| URL الوصول: | https://doaj.org/article/4533eabcc6a84f10bd65b360fcfcdc66 |
| رقم الانضمام: | edsdoj.4533eabcc6a84f10bd65b360fcfcdc66 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22131582 |
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| DOI: | 10.1016/j.nicl.2018.101613 |