Academic Journal
Study on thermostabilizers for trivalent oral poliomyelitis vaccine
| العنوان: | Study on thermostabilizers for trivalent oral poliomyelitis vaccine |
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| المؤلفون: | M. L. F. Leal, F. J. C. Lopes, M. H. G. Carvalho, H. A. B. Moura, S. A. F. Soares |
| المصدر: | Memorias do Instituto Oswaldo Cruz, Vol 85, Iss 3, Pp 329-338 (1990) |
| بيانات النشر: | Fundação Oswaldo Cruz (FIOCRUZ), 1990. |
| سنة النشر: | 1990 |
| المجموعة: | LCC:Microbiology LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | poliovaccine, thermostabilizers, Microbiology, QR1-502, Infectious and parasitic diseases, RC109-216 |
| الوصف: | Different formulations of trivalent oral poliomyelitis vaccine were tested, in order to obtain better thermostability, reduce corrosion of machinery and improve production costs. Magnesium chloride, sucrose, arginine and 199-Hank's medium were used in the formulations. The most appropriate formulation was a mixture of MgCl2 and arginine, which was highly thermostable, and had low production costs. The low corrosive formulation was rejected, due to low thermostability on storage. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0074-0276 1678-8060 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761990000300010; https://doaj.org/toc/0074-0276; https://doaj.org/toc/1678-8060 |
| DOI: | 10.1590/S0074-02761990000300010 |
| URL الوصول: | https://doaj.org/article/442b15c8d6244b53ac03f297a16efcdb |
| رقم الانضمام: | edsdoj.442b15c8d6244b53ac03f297a16efcdb |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 00740276 16788060 |
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| DOI: | 10.1590/S0074-02761990000300010 |