Academic Journal

Transcatheter Closure or Surgery for Symptomatic Paravalvular Leaks: The Multicenter KISS Registry

التفاصيل البيبلوغرافية
العنوان: Transcatheter Closure or Surgery for Symptomatic Paravalvular Leaks: The Multicenter KISS Registry
المؤلفون: Ahmet Güner, Cevat Kırma, Mehmet Ertürk, Muhsin Türkmen, Gökhan Alıcı, Can Yücel Karabay, Fatih Uzun, Alev Kılıçgedik, Sabahattin Gündüz, Gamze Babur Güler, Ali Kemal Kalkan, Birol Özkan, Münevver Sarı, Mustafa Ozan Gürsoy, Meltem Tekin, Mustafa Yıldız, Fatma Can, Kaan Kırali, Ali Fedakar, Sabit Sarıkaya, Ünal Aydın, Serkan Kahraman, Taner İyigün, Mehmet Aksüt, Eren Karpuzoğlu, Koray Çiloğlu, Mustafa Azmi Sungur, İbrahim Halil Tanboğa, Mehmet Özkan
المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 1 (2024)
بيانات النشر: Wiley, 2024.
سنة النشر: 2024
المجموعة: LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: death, echocardiography, paravalvular leak, surgery, transcatheter closure, Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Background The optimal treatment of symptomatic paravalvular leak (PVL) remains controversial between transcatheter closure (TC) and surgery. This large‐scale study aimed to retrospectively evaluate the long‐term outcomes of the patients who underwent reoperation or TC of PVLs. Methods and Results A total of 335 (men, 209 [62.4%]; mean age, 58.15±12.77 years) patients who underwent treatment of PVL at 3 tertiary centers between January 2002 and December 2021 were included. Echocardiographic features, procedure details, and in‐hospital or long‐term outcomes were assessed. The primary end point was defined as the all‐cause death during follow‐up. The regression models were adjusted by applying the inverse probability weighted approach to reduce treatment selection bias. The initial management strategy was TC in 171 (51%) patients and surgery in 164 (49%) cases. Three hundred cases (89.6%) had mitral PVL, and 35 (10.4%) had aortic PVL. The mean left ventricular ejection fraction was 52.03±10.79%. Technical (78.9 versus 76.2%; P=0.549) and procedural success (73.7 versus 65.2%; P=0.093) were similar between both groups. In both univariate and multivariable logistic regression analysis, the in‐hospital mortality rate in the overall population was significantly higher (15.9 versus 4.7%) in the surgery group compared with the TC group (unadjusted odds ratio, 3.13 [95% CI, 1.75–5.88]; P=0.001; and adjusted odds ratio (inverse probability‐weighted), 4.55 [95% CI, 2.27–10.0]; P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2047-9980
Relation: https://doaj.org/toc/2047-9980
DOI: 10.1161/JAHA.123.032262
URL الوصول: https://doaj.org/article/438486624f264074ad4cce33e84000c3
رقم الانضمام: edsdoj.438486624f264074ad4cce33e84000c3
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20479980
DOI:10.1161/JAHA.123.032262