Academic Journal

Depressive disorder and elevated risk of bell’s palsy: a nationwide propensity score-weighting study

التفاصيل البيبلوغرافية
العنوان: Depressive disorder and elevated risk of bell’s palsy: a nationwide propensity score-weighting study
المؤلفون: Li-Yun Fann, Yuan-Liang Wen, Yu-Chieh Huang, Chih-Chien Cheng, Ying-Che Huang, Chih-Chia Fang, Wan-Ting Chen, Pei-Yeh Yu, Hsiang-Yi Pan, Li-Ting Kao
المصدر: BMC Psychiatry, Vol 24, Iss 1, Pp 1-9 (2024)
بيانات النشر: BMC, 2024.
سنة النشر: 2024
المجموعة: LCC:Psychiatry
مصطلحات موضوعية: Depressive Disorder, Bell's palsy, Facial nerve paralysis, Risk factors, Psychiatry, RC435-571
الوصف: Abstract Background Prior studies have reported a potential relationship between depressive disorder (DD), immune function, and inflammatory response. Some studies have also confirmed the correlation between immune and inflammatory responses and Bell’s palsy. Considering that the pathophysiology of these two diseases has several similarities, this study investigates if DD raises the risk of developing Bell’s palsy. Methods This nationwide propensity score-weighting cohort study utilized Taiwan National Health Insurance data. 44,198 patients with DD were identified as the DD cohort and 1,433,650 adult subjects without DD were identified as the comparison cohort. The inverse probability of treatment weighting (IPTW) strategy was used to balance the differences of covariates between two groups. The 5-year incidence of Bell’s palsy was evaluated using the Cox proportional-hazard model, presenting results in terms of hazard ratios (HRs) and 95% confidence intervals (CIs). Results The average age of DD patients was 48.3 ± 17.3 years, and 61.86% were female. After propensity score-weighting strategy, no significant demographic differences emerged between the DD and comparison cohort. The Cox proportional hazards model revealed a statistically significant adjusted IPTW-HR of 1.315 (95% CI: 1.168–1.481) for Bell’s palsy in DD patients compared to comparison subjects. Further independent factors for Bell’s palsy in this model were age (IPTW-HR: 1.012, 95% CI: 1.010–1.013, p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-244X
Relation: https://doaj.org/toc/1471-244X
DOI: 10.1186/s12888-024-05730-2
URL الوصول: https://doaj.org/article/42e2a4f7d5014bea9406f5ff20ad23d5
رقم الانضمام: edsdoj.42e2a4f7d5014bea9406f5ff20ad23d5
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1471244X
DOI:10.1186/s12888-024-05730-2