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Fresh Insights Into SLC25A26: Potential New Therapeutic Target for Cancers: A Review

التفاصيل البيبلوغرافية
العنوان: Fresh Insights Into SLC25A26: Potential New Therapeutic Target for Cancers: A Review
المؤلفون: Yangheng Xu, Zhisheng Hong, Sheng Yu, Ronghan Huang, Kunqi Li, Ming Li, Sisi Xie, Lvyun Zhu
المصدر: Oncology Reviews, Vol 18 (2024)
بيانات النشر: Frontiers Media S.A., 2024.
سنة النشر: 2024
المجموعة: LCC:Other systems of medicine
LCC:Internal medicine
مصطلحات موضوعية: SLC25A26, S-adenosylmethionine carrier protein, cancer, gene expression regulation, methylation, Other systems of medicine, RZ201-999, Internal medicine, RC31-1245
الوصف: SLC25A26 is the only known human mitochondrial S-adenosylmethionine carrier encoding gene. Recent studies have shown that SLC25A26 is abnormally expressed in some cancers, such as cervical cancer, low-grade glioma, non-small cell lung cancer, and liver cancer, which suggests SLC25A26 can affect the occurrence and development of some cancers. This article in brief briefly reviewed mitochondrial S-adenosylmethionine carrier in different species and its encoding gene, focused on the association of SLC25A26 aberrant expression and some cancers as well as potential mechanisms, summarized its potential for cancer prognosis, and characteristics of mitochondrial diseases caused by SLC25A26 mutation. Finally, we provide a brief expectation that needs to be further investigated. We speculate that SLC25A26 will be a potential new therapeutic target for some cancers.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1970-5557
Relation: https://www.frontiersin.org/articles/10.3389/or.2024.1379323/full; https://doaj.org/toc/1970-5557
DOI: 10.3389/or.2024.1379323
URL الوصول: https://doaj.org/article/e421bf6ad6f54b16ba93dd7a3224f52b
رقم الانضمام: edsdoj.421bf6ad6f54b16ba93dd7a3224f52b
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19705557
DOI:10.3389/or.2024.1379323