التفاصيل البيبلوغرافية
العنوان: |
Durable protection against repeated penile exposures to simian-human immunodeficiency virus by broadly neutralizing antibodies |
المؤلفون: |
David A. Garber, Debra R. Adams, Patricia Guenthner, James Mitchell, Kristen Kelley, Till Schoofs, Anna Gazumyan, Martha Nason, Michael S. Seaman, Janet McNicholl, Michel C. Nussenzweig, Walid Heneine |
المصدر: |
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020) |
بيانات النشر: |
Nature Portfolio, 2020. |
سنة النشر: |
2020 |
المجموعة: |
LCC:Science |
مصطلحات موضوعية: |
Science |
الوصف: |
Here, using a repeat-exposure penile SHIV infection model in macaques, the authors show that a single subcutaneous administration of a broadly neutralizing antibody (bNAb) exerts long-acting protection against both penile and vaginal virus exposure, which highlights bNAbs as a potential therapeutic for LA-PrEP. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-020-16928-9 |
URL الوصول: |
https://doaj.org/article/415ea2495b55415ba7d408c549af42a5 |
رقم الانضمام: |
edsdoj.415ea2495b55415ba7d408c549af42a5 |
قاعدة البيانات: |
Directory of Open Access Journals |