التفاصيل البيبلوغرافية
| العنوان: |
Quantitative characterization of recombinase-based digitizer circuits enables predictable amplification of biological signals |
| المؤلفون: |
Katherine A. Kiwimagi, Justin H. Letendre, Benjamin H. Weinberg, Junmin Wang, Mingzhe Chen, Leandro Watanabe, Chris J. Myers, Jacob Beal, Wilson W. Wong, Ron Weiss |
| المصدر: |
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021) |
| بيانات النشر: |
Nature Portfolio, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Biology (General) |
| مصطلحات موضوعية: |
Biology (General), QH301-705.5 |
| الوصف: |
Kiwimagi & Letendre et al. present a workflow to quantitatively define recombinase-based digitizer and predict responses to different input signals. With a mechanistic/phenotypic model that can predict circuit performance, they generate a synthetic cell-cell communication device that amplifies a synNotch output signal. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2399-3642 |
| Relation: |
https://doaj.org/toc/2399-3642 |
| DOI: |
10.1038/s42003-021-02325-5 |
| URL الوصول: |
https://doaj.org/article/d4030bb1a2c34df186adb664ad87a908 |
| رقم الانضمام: |
edsdoj.4030bb1a2c34df186adb664ad87a908 |
| قاعدة البيانات: |
Directory of Open Access Journals |
Full Text Finder