التفاصيل البيبلوغرافية
| العنوان: |
Ion currents through Kir potassium channels are gated by anionic lipids |
| المؤلفون: |
Ruitao Jin, Sitong He, Katrina A. Black, Oliver B. Clarke, Di Wu, Jani R. Bolla, Paul Johnson, Agalya Periasamy, Ahmad Wardak, Peter Czabotar, Peter M. Colman, Carol V. Robinson, Derek Laver, Brian J. Smith, Jacqueline M. Gulbis |
| المصدر: |
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022) |
| بيانات النشر: |
Nature Portfolio, 2022. |
| سنة النشر: |
2022 |
| المجموعة: |
LCC:Science |
| مصطلحات موضوعية: |
Science |
| الوصف: |
The Kir potassium channels are known to operate and gate without a major conformational change. Here, the authors identify the permeation gate of Kir channels as a steric plug within the conduction pathway, describing how tightly associated anionic lipids pushing into fenestrations in the pore walls engage with the plug to operate the gate. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-022-28148-4 |
| URL الوصول: |
https://doaj.org/article/400ab475f64247199cf3b4d67129ff32 |
| رقم الانضمام: |
edsdoj.400ab475f64247199cf3b4d67129ff32 |
| قاعدة البيانات: |
Directory of Open Access Journals |
Full Text Finder