Academic Journal
Cancer as a System Dysfunction
العنوان: | Cancer as a System Dysfunction |
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المؤلفون: | Khalid Saeed, Elizabeth F. Ryder, Amity L. Manning |
المصدر: | Systems, Vol 9, Iss 1, p 14 (2021) |
بيانات النشر: | MDPI AG, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Systems engineering LCC:Technology (General) |
مصطلحات موضوعية: | cancer, system, system dynamics, biology, cancer biology, computational biology, Systems engineering, TA168, Technology (General), T1-995 |
الوصف: | In this paper, we describe a system dynamics model that views cancer as a dysfunction of the cellular system rather than as an ailment of cells. Our experiments with the model replicate the propagation of the ailment and the impacts of the treatments. It presents a concept that deviates from the pervasive view of cancer as a cell malfunction that has led to treatments aiming to destroy the rogue cells. It points to more holistic treatment options aiming at reforming cell interaction so the system can contain the growth of cancer cells. Further research is needed to explore the details for such options. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2079-8954 |
Relation: | https://www.mdpi.com/2079-8954/9/1/14; https://doaj.org/toc/2079-8954 |
DOI: | 10.3390/systems9010014 |
URL الوصول: | https://doaj.org/article/3f4e09c0ec624c709b934c4ce89a38be |
رقم الانضمام: | edsdoj.3f4e09c0ec624c709b934c4ce89a38be |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20798954 |
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DOI: | 10.3390/systems9010014 |