Academic Journal
Individuals with anxiety and depression use atypical decision strategies in an uncertain world
| العنوان: | Individuals with anxiety and depression use atypical decision strategies in an uncertain world |
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| المؤلفون: | Zeming Fang, Meihua Zhao, Ting Xu, Yuhang Li, Hanbo Xie, Peng Quan, Haiyang Geng, Ru-Yuan Zhang |
| المصدر: | eLife, Vol 13 (2024) |
| بيانات النشر: | eLife Sciences Publications Ltd, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Science LCC:Biology (General) |
| مصطلحات موضوعية: | probabilistic reversal learning, depression, anxiety, mixed decision strategy, heuristic strategy, environmental volatility, Medicine, Science, Biology (General), QH301-705.5 |
| الوصف: | Previous studies on reinforcement learning have identified three prominent phenomena: (1) individuals with anxiety or depression exhibit a reduced learning rate compared to healthy subjects; (2) learning rates may increase or decrease in environments with rapidly changing (i.e. volatile) or stable feedback conditions, a phenomenon termed learning rate adaptation; and (3) reduced learning rate adaptation is associated with several psychiatric disorders. In other words, multiple learning rate parameters are needed to account for behavioral differences across participant populations and volatility contexts in this flexible learning rate (FLR) model. Here, we propose an alternative explanation, suggesting that behavioral variation across participant populations and volatile contexts arises from the use of mixed decision strategies. To test this hypothesis, we constructed a mixture-of-strategies (MOS) model and used it to analyze the behaviors of 54 healthy controls and 32 patients with anxiety and depression in volatile reversal learning tasks. Compared to the FLR model, the MOS model can reproduce the three classic phenomena by using a single set of strategy preference parameters without introducing any learning rate differences. In addition, the MOS model can successfully account for several novel behavioral patterns that cannot be explained by the FLR model. Preferences for different strategies also predict individual variations in symptom severity. These findings underscore the importance of considering mixed strategy use in human learning and decision-making and suggest atypical strategy preference as a potential mechanism for learning deficits in psychiatric disorders. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2050-084X |
| Relation: | https://elifesciences.org/articles/93887; https://doaj.org/toc/2050-084X |
| DOI: | 10.7554/eLife.93887 |
| URL الوصول: | https://doaj.org/article/3f0855d82d094bbfa0b867349ee207e4 |
| رقم الانضمام: | edsdoj.3f0855d82d094bbfa0b867349ee207e4 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2050084X |
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| DOI: | 10.7554/eLife.93887 |