Academic Journal
7.9 CAROTID ARTERY STIFFNESS IS ASSOCIATED WITH CT-MEASURED LUNG AIR-TRAPPING IN COPD PATIENTS AND CONTROLS INDEPENDENT OF AGE, BLOOD PRESSURE AND SMOKING HISTORY
| العنوان: | 7.9 CAROTID ARTERY STIFFNESS IS ASSOCIATED WITH CT-MEASURED LUNG AIR-TRAPPING IN COPD PATIENTS AND CONTROLS INDEPENDENT OF AGE, BLOOD PRESSURE AND SMOKING HISTORY |
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| المؤلفون: | Gary Pierce, John Newell, Alejandro Comellas, Eric Hoffman, Kelsey Warner, Anna Croghan, Lyndsey DuBose, Peg Nopoulos, Vince Magnotta, Stephan Arndt, Karin Hoth |
| المصدر: | Artery Research, Vol 16 (2016) |
| بيانات النشر: | BMC, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Specialties of internal medicine LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | Specialties of internal medicine, RC581-951, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Background: Early stages of chronic obstructive pulmonary disease (COPD) are characterized by loss of the terminal bronchioles and ‘air trapping’ often before overt emphysema manifests (1). COPD patients are also at risk for cardiovascular disease (CVD), therefore, we hypothesized that the degree of air trapping on computed tomography (CT) (2) would be associated with higher aortic (carotid femoral pulse wave velocity, CFPWV) and carotid artery stiffness (β-stiffness), biomarkers of CVD risk. Methods: Ten adults with COPD but little emphysema (age 66±8 yrs, 5F/5M, GOLD stage 1–3) and 9 adults without COPD (age 59±13 yrs, 5F/4M) that had a research chest CT were recruited. Results: COPD patients had greater smoking history (45.9 ± 21 vs. 6.4 ± 12.9 pack-years, P0.05). COPD patients had significantly higher CFPWV (999± 293 vs. 760 ±147 cm/sec, p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1876-4401 |
| Relation: | https://www.atlantis-press.com/article/125930421/view; https://doaj.org/toc/1876-4401 |
| DOI: | 10.1016/j.artres.2016.10.055 |
| URL الوصول: | https://doaj.org/article/3ec592a5b5d94bc4a6d4a867bb07276d |
| رقم الانضمام: | edsdoj.3ec592a5b5d94bc4a6d4a867bb07276d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18764401 |
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| DOI: | 10.1016/j.artres.2016.10.055 |