Academic Journal
Efficacy of different modes of pharmacotherapy for men with lower urinary tract symptoms benign prostatic hyperplasia depending of androgenic status
| العنوان: | Efficacy of different modes of pharmacotherapy for men with lower urinary tract symptoms benign prostatic hyperplasia depending of androgenic status |
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| المؤلفون: | O. I. Bratchikov, I. A. Tyuzikov, E. A. Scumakova, V. V. Elagin, S. O. Artishchev |
| المصدر: | Андрология и генитальная хирургия, Vol 17, Iss 4, Pp 21-27 (2017) |
| بيانات النشر: | ABV-press, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Surgery LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: | lower urinary tract symptoms, benign prostatic hyperplasia, late-onset androgen deficiency, hypogonadism, pharmacotherapy, testosterone undecanoate, Surgery, RD1-811, Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: | In a sample of 187 men (average age of 65,3 ± 3,2 years) conducted a comparative analysis of clinical and urodynamic efficacy and safety of different modes of pharmacotherapy (monotherapy, α-1 blocker (n = 40), 5-α-reductase inhibitor (n = 35), plant agent (n = 30), combination therapy α-1 blocker + 5-α-reductase inhibitor with additional androgen replacement therapy (ART) with testosterone undecanoate (n = 42) and without ART (n = 40)) in men with lower urinary tract symptoms benign prostatic hyperplasia (LUTS/BPH) depending on their androgenic status within 24 months. Efficiency standard pharmacotherapy for patients with LUTS/BPH without their androgenic status with proper selection of drugs averaged 70.2 %, the effects of monotherapy with α-1 adrenoblocker averaged 62.7 %, with 5-α-reductase inhibitor – 78.4 %, plant agent – 49.3 %, respectively (p < 0.05). The most effective type of treatment of LUTS/BPH in men regardless of their status was combination therapy with α-1 blockers and 5-α-reductase inhibitors, the effectiveness of which reached 82.4 % (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 2070-9781 |
| Relation: | https://agx.abvpress.ru/jour/article/view/209; https://doaj.org/toc/2070-9781 |
| DOI: | 10.17650/2070-9781-2016-17-4-21-27 |
| URL الوصول: | https://doaj.org/article/3d528e4dec7541768793439290f60bbf |
| رقم الانضمام: | edsdoj.3d528e4dec7541768793439290f60bbf |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 20709781 |
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| DOI: | 10.17650/2070-9781-2016-17-4-21-27 |