Academic Journal

Supplementation of cassava fiber counteracts high sugar diet-induced metabolic syndromes by maintaining glucose and lipid homeostasis

التفاصيل البيبلوغرافية
العنوان: Supplementation of cassava fiber counteracts high sugar diet-induced metabolic syndromes by maintaining glucose and lipid homeostasis
المؤلفون: Rakhi Chacrabati, Md. Kamrul Hasan Kazal, Ohi Alam, Romana Jahan Moon, Khadiza Khatun, Chayon Goswami
المصدر: Fundamental and Applied Agriculture, Vol 7, Iss 2, Pp 94-103 (2022)
بيانات النشر: Farm to Fork Foundation, 2022.
سنة النشر: 2022
المجموعة: LCC:Agriculture
مصطلحات موضوعية: cassava, dietary fiber, high sugar diet, diabetes, obesity, Agriculture
الوصف: Metabolic disorders characterized by different physiological syndromes are affecting modern society, particularly the people who live in urban areas. High sugar diet (HSD) consumption is associated with the development of metabolic diseases such as diabetes and obesity. Dietary fiber has been linked to a variety of health benefits, including obesity prevention, better glucose homeostasis, and control of blood lipid profile. Therefore, we designed this experiment to determine the efficacy of cassava fiber (CF) in preventing the development of diabetes and obesity caused by HSD. Swiss albino male mice were fed with CF in supplementation with or without HSD. In comparison to a high sugar diet group, CF supplementation steadily reduced food intake. Though it was insignificant CF supplementation attenuated the increase in body weight due to HSD consumption. From the intraperitoneal glucose tolerance test (ipGTT), it was revealed that CF supplementation improved glucose tolerance after a glucose (2mg/kg BW) challenge and also showed a significant decrease in area under the curve (AUC). Moreover, CF supplementation remarkably lowered the LDL-cholesterol level of the HSD-fed mice. Overall, our present study demonstrates that consumption of a CF-rich diet helps to maintain glucose homeostasis and prevent the development of metabolic syndromes associated with diabetes and obesity. [Fundam Appl Agric 2022; 7(2.000): 94-103]
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2518-2021
Relation: http://www.ejmanager.com/fulltextpdf.php?mno=41875; https://doaj.org/toc/2518-2021
DOI: 10.5455/faa.41875
URL الوصول: https://doaj.org/article/d3d3f5fa063f432e8406821d42ad9923
رقم الانضمام: edsdoj.3d3f5fa063f432e8406821d42ad9923
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:25182021
DOI:10.5455/faa.41875