Academic Journal

Macrophage-specific RAM11 monoclonal antibody cross-reacts with basal cells of stratified squamous epithelia.

التفاصيل البيبلوغرافية
العنوان: Macrophage-specific RAM11 monoclonal antibody cross-reacts with basal cells of stratified squamous epithelia.
المؤلفون: Tadeusz Cichocki, Joanna Zarzecka, Alicja Furgal-Borzych, Jan A Litwin, Grzegorz J Lis
المصدر: Folia Histochemica et Cytobiologica, Vol 45, Iss 3, Pp 229-232 (2007)
بيانات النشر: Via Medica, 2007.
سنة النشر: 2007
المجموعة: LCC:Cytology
مصطلحات موضوعية: Cytology, QH573-671
الوصف: RAM11 is a mouse monoclonal anti-rabbit macrophage antibody recognizing connective tissue and vascular (atheromatous tissue) macrophages. This study demonstrates a cross-reaction of RAM11 with an unknown antigen in rabbit normal epithelial cells. Formalin-fixed, paraffin sections of the New Zealand White rabbit normal skin, oral mucosa, esophagus, small intestine and lung were immunostained with RAM11 antibody followed by goat anti-mouse Cy-3-conjugated antiglobulin. RAM11-positive immunofluorescence was observed in basal layer cells of stratified squamous epithelia (skin, oral mucosa, esophagus). No RAM11 immunostaining was found in any cells of simple (intestinal, bronchial) epithelia. These findings show that basal cells of stratified squamous keratinized and non-keratinized epithelia of the rabbit express an antigenic epitope which is common with that of macrophage antigen recognized by RAM11 monoclonal antibody.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0239-8508
1897-5631
Relation: http://czasopisma.viamedica.pl/fhc/article/view/4528; https://doaj.org/toc/0239-8508; https://doaj.org/toc/1897-5631
DOI: 10.5603/4528
URL الوصول: https://doaj.org/article/c3d3d6c0c03a4cc187f08da4e38b2f96
رقم الانضمام: edsdoj.3d3d6c0c03a4cc187f08da4e38b2f96
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:02398508
18975631
DOI:10.5603/4528