التفاصيل البيبلوغرافية
| العنوان: |
Case Report: Hyperinflammatory Status in an Immunocompromised Child With a Highly Sustained Viral Load of SARS-CoV-2 |
| المؤلفون: |
Matias Moragas, Sandra Gomez, María Florencia Fernández, Marcelo Dario Golemba, Marcela Palladino, Daniela Borgnia, Silvina Ruvinsky, Lidia Fraquelli, Ana Buchovsky, Rosa Bologna, Andrea Mangano |
| المصدر: |
Frontiers in Medicine, Vol 8 (2021) |
| بيانات النشر: |
Frontiers Media S.A., 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Medicine (General) |
| مصطلحات موضوعية: |
SARS-CoV-2, COVID-19, viral load, immunocompromised state, hyperinflammatory status, pediatrics, Medicine (General), R5-920 |
| الوصف: |
Coronavirus disease 2019 (COVID-19) is spreading throughout the world. Limited data are available for the dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load (VL) in immunocompromised pediatric patients. Here, we report the clinical characteristics and the dynamics of SARS-CoV-2 VL of a pediatric patient with acute myeloid leukemia who developed a hyperinflammatory status mimicked MIS-C. The clinical course was characterized by the late onset of fever, GI symptoms, rash, and respiratory distress, including oxygen requirement with sustained VL of SARS-CoV-2 around 7 log10 RNA copies/mL for 6 weeks. It is important to note that the hyperinflammatory status developed early at the third week of hospitalization—in a context of high VL and immunocompromised status. All these characteristics make this clinical case unique. On the other hand, while many reports have characterized the dynamics of SARS-CoV-2 VL in adults and immunocompetent hosts, it remains unreported in pediatrics—even less in immunosuppressed children. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2296-858X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fmed.2021.675282/full; https://doaj.org/toc/2296-858X |
| DOI: |
10.3389/fmed.2021.675282 |
| URL الوصول: |
https://doaj.org/article/3ced55d9e2be43f0bd0cbcf38820200d |
| رقم الانضمام: |
edsdoj.3ced55d9e2be43f0bd0cbcf38820200d |
| قاعدة البيانات: |
Directory of Open Access Journals |
Full Text Finder