Academic Journal

Transcriptomic response of lumpfish (Cyclopterus lumpus) head kidney to viral mimic, with a focus on the interferon regulatory factor family

التفاصيل البيبلوغرافية
العنوان: Transcriptomic response of lumpfish (Cyclopterus lumpus) head kidney to viral mimic, with a focus on the interferon regulatory factor family
المؤلفون: Mohamed Emam, Surendra Kumar, Khalil Eslamloo, Albert Caballero-Solares, Jennifer R. Hall, Xi Xue, Hélène Paradis, Robert L. Gendron, Javier Santander, Matthew L. Rise
المصدر: Frontiers in Immunology, Vol 15 (2024)
بيانات النشر: Frontiers Media S.A., 2024.
سنة النشر: 2024
المجموعة: LCC:Immunologic diseases. Allergy
مصطلحات موضوعية: antiviral, lumpfish (Cyclopterus lumpus), IRF, RNA seq, qPCR, Immunologic diseases. Allergy, RC581-607
الوصف: The economic importance of lumpfish (Cyclopterus lumpus) is increasing, but several aspects of its immune responses are not well understood. To discover genes and mechanisms involved in the lumpfish antiviral response, fish were intraperitoneally injected with either the viral mimic polyinosinic:polycytidylic acid [poly(I:C)] or phosphate-buffered saline (PBS; vehicle control), and head kidneys were sampled 24 hours post-injection (hpi) for transcriptomic analyses. RNA sequencing (RNA-Seq) (adjusted p-value
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1664-3224
Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1439465/full; https://doaj.org/toc/1664-3224
DOI: 10.3389/fimmu.2024.1439465
URL الوصول: https://doaj.org/article/3c8bae8f299840aebfc6a9e7e56273d9
رقم الانضمام: edsdoj.3c8bae8f299840aebfc6a9e7e56273d9
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16643224
DOI:10.3389/fimmu.2024.1439465