Academic Journal
Granulomatous amebic encephalitis in a patient treated with chemotherapy: a case report and literature review
| العنوان: | Granulomatous amebic encephalitis in a patient treated with chemotherapy: a case report and literature review |
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| المؤلفون: | Marcos R. Flores, Miranda G. Montion, Aneesha N. Usman, Munachiso A. Ngene, Samir Ruxmohan |
| المصدر: | Journal of Neurocritical Care, Vol 17, Iss 2, Pp 88-93 (2024) |
| بيانات النشر: | The Korean Neurocritical Care Society, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Neurology. Diseases of the nervous system |
| مصطلحات موضوعية: | immunocompromised host, amebiasis, central nervous system infections, encephalitis, critical care, neurology, Neurology. Diseases of the nervous system, RC346-429 |
| الوصف: | Background Granulomatous amebic encephalitis (GAE) is caused by Acanthamoeba species or Balamuthia mandrillaris, which are microscopic, free-living amoebas found worldwide. People with compromised immune systems are at an increased risk of fatal cerebral infection caused by Acanthamoeba species, whereas B. mandrillaris can affect both immunocompromised and immunocompetent patients. Infections can involve the central nervous system causing GAE. Case Report A 71-year-old Caucasian woman, previously diagnosed with chronic lymphocytic leukemia and undergoing chemotherapy, arrived at the emergency department exhibiting seizure-like symptoms. Brain imaging revealed bilateral cerebral masses with central necrosis and hemorrhage, among other findings. The patient underwent a biopsy and was diagnosed with GAE. Conclusion Unfortunately, even with the correct diagnosis, GAE leads to rapid deterioration and a higher risk of mortality. This case demonstrates the rapid and severe nature of GAE and emphasizes the need for ongoing studies and better treatment options to improve GAE outcomes. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Korean |
| تدمد: | 2005-0348 2508-1349 |
| Relation: | http://e-jnc.org/upload/pdf/jnc-240032.pdf; https://doaj.org/toc/2005-0348; https://doaj.org/toc/2508-1349 |
| DOI: | 10.18700/jnc.240032 |
| URL الوصول: | https://doaj.org/article/3bbdd65c9c9c48e082d0e9ea50d16c3c |
| رقم الانضمام: | edsdoj.3bbdd65c9c9c48e082d0e9ea50d16c3c |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 20050348 25081349 |
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| DOI: | 10.18700/jnc.240032 |