Academic Journal

SARS-CoV-2 infection in high-risk children following tixagevimab–cilgavimab (Evusheld) pre-exposure prophylaxis: a single-center observational study

التفاصيل البيبلوغرافية
العنوان: SARS-CoV-2 infection in high-risk children following tixagevimab–cilgavimab (Evusheld) pre-exposure prophylaxis: a single-center observational study
المؤلفون: Diego R. Hijano, Jose A. Ferrolino, Elizabeth G. Swift, Carolyn A. Michaels, Anita Max, Randall T. Hayden, Joshua Wolf, Ronald H. Dallas, William L. Greene, Julie L. Richardson, Hana Hakim, Ted H. Morton, Shane J. Cross
المصدر: Frontiers in Oncology, Vol 13 (2023)
بيانات النشر: Frontiers Media S.A., 2023.
سنة النشر: 2023
المجموعة: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
مصطلحات موضوعية: coronavirus, immunocompromised, cancer, hematopoietic cell transplant, monoclonal antibodies, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: From 8 December 2021 to 26 January 2023, tixagevimab–cilgavimab (T-C) was authorized for pre-exposure prophylaxis of COVID-19. During this period, we used a multidisciplinary team to communicate, screen, approach, and administer T-C to eligible patients. Twenty-seven patients were eligible. Of these, 24 (88.9%) received at least one dose of T-C and three patients received two doses. Majority of patients were White, non-Hispanic, and women. Only two patients had COVID-19 prior to receiving T-C. Seventeen (70.8%) had received two or more doses of SARS-CoV-2 vaccine. No serious adverse events were noted. Seven patients developed SARS-CoV-2 infection within 180 days of receiving T-C (median 102 days; range 28–135), and only one patient developed severe COVID-19 requiring intensive mechanical ventilation in the intensive care unit.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2234-943X
Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1229655/full; https://doaj.org/toc/2234-943X
DOI: 10.3389/fonc.2023.1229655
URL الوصول: https://doaj.org/article/3b3fa89f9b9d4168af093e8690871059
رقم الانضمام: edsdoj.3b3fa89f9b9d4168af093e8690871059
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:2234943X
DOI:10.3389/fonc.2023.1229655