التفاصيل البيبلوغرافية
| العنوان: |
CONTRIBUTION OF APICAL DENDRITES TO RECEPTIVE FIELD PROPERTIES IN LAYER 2/3 OF MOUSE V1 |
| المؤلفون: |
Jiyoung Park, Stelios Manolis Smirnakis |
| المصدر: |
Frontiers in Systems Neuroscience, Vol 8 (2014) |
| بيانات النشر: |
Frontiers Media S.A., 2014. |
| سنة النشر: |
2014 |
| المجموعة: |
LCC:Neurosciences. Biological psychiatry. Neuropsychiatry |
| مصطلحات موضوعية: |
pyramidal neuron, orientation selectivity, in vivo two photon imaging, Mouse V1, apidal dendrite, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571 |
| الوصف: |
Although slice recordings and model studies provide a lot of information about how neurons integrate their inputs to overall responses, it is still not clear how neurons in the brain integrate their synaptic inputs to derive their functional properties in vivo. Pyramidal neurons in layer 2/3 of mouse V1 receive input from LGN via layer 4 and feedback from higher visual areas. Here, we focus on the function of apical dendrites, which play an important role in communicating with higher visual areas. We ablate apical dendrites of layer 2/3 pyramidal neurons in area V1, in vivo, and monitor their responses to visual stimuli by two photon microscopy. We compare orientation selectivity, contrast sensitivity and other receptive field properties of L2/3 pyramidal neurons before and after selective apical dendritic ablation. This approach provides information on how different dendritic inputs contribute to neuronal receptive field properties of L2/3 pyramidal neurons in mouse V1. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1662-5137 |
| Relation: |
http://journal.frontiersin.org/Journal/10.3389/conf.fnsys.2014.05.00046/full; https://doaj.org/toc/1662-5137 |
| DOI: |
10.3389/conf.fnsys.2014.05.00046 |
| URL الوصول: |
https://doaj.org/article/39cbfc70fad2490399acc329696fadbc |
| رقم الانضمام: |
edsdoj.39cbfc70fad2490399acc329696fadbc |
| قاعدة البيانات: |
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