Academic Journal
Calcium Binding Proteins]
| العنوان: | Calcium Binding Proteins] |
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| المؤلفون: | Berivan Tandoğan, N. Nuray Ulusu |
| المصدر: | Türk Biyokimya Dergisi, Vol 31, Iss 1, Pp 36-40 (2006) |
| بيانات النشر: | De Gruyter, 2006. |
| سنة النشر: | 2006 |
| المجموعة: | LCC:Biochemistry |
| مصطلحات موضوعية: | Calcium binding proteins, calmodulin, S100 protein family, annexins, Biochemistry, QD415-436 |
| الوصف: | ABSTRACTCalcium ions are essentail for some of the cellular functions, including musclecontraction, adhesion, secretion, motility, growth, differentiation, gene expression,and cell death. The change in calcium concentration is transmitted as a signal ofthe intracellular second messenger. Calcium binding proteins are the mediators ofthe signal, and play pivotal roles in the many cellular processes through a varietyof different mechanisms. Calcium binding proteins are also an important molecularchaperones involved in the protein synthesis within secretory pathways. Theirmajor role is assumed to be buffering, transport of calcium, and regulation of variousenzyme systems. Calcium binding proteins have remarkable sequence homologyand structural similarity, yet they function in a wide range of biologicalprocesses. Several important disease states; hypertension, heart disease, diabetes,manic depression, Alzheimer’s disease may result from abnormal remodeling ofcalcium binding proteins. It has been found that several calcium binding proteinshave important roles in cell survival and apoptosis pathways and may also promotecancer progression. Because of the levels of calcium binding protein expressionhas changed in different stages and types of cancer, these proteins can be used ascancer markers. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0250-4685 1303-829X |
| Relation: | http://www.turkjbiochem.com/2006/036_040.pdf; https://doaj.org/toc/0250-4685; https://doaj.org/toc/1303-829X |
| URL الوصول: | https://doaj.org/article/398b200207f94e1faf14e44bdd47b274 |
| رقم الانضمام: | edsdoj.398b200207f94e1faf14e44bdd47b274 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 02504685 1303829X |
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