Academic Journal
Aspirin use for primary prevention among US adults with and without elevated Lipoprotein(a)
العنوان: | Aspirin use for primary prevention among US adults with and without elevated Lipoprotein(a) |
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المؤلفون: | Alexander C. Razavi, LaTonia C. Richardson, Fátima Coronado, Omar Dzaye, Harpreet S. Bhatia, Anurag Mehta, Arshed A. Quyyumi, Viola Vaccarino, Matthew J. Budoff, Khurram Nasir, Sotirios Tsimikas, Seamus P. Whelton, Michael J. Blaha, Roger S. Blumenthal, Laurence S. Sperling |
المصدر: | American Journal of Preventive Cardiology, Vol 18, Iss , Pp 100674- (2024) |
بيانات النشر: | Elsevier, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system LCC:Public aspects of medicine |
مصطلحات موضوعية: | Lipoprotein(a), Aspirin, Cardiovascular disease, NHANES, Diseases of the circulatory (Cardiovascular) system, RC666-701, Public aspects of medicine, RA1-1270 |
الوصف: | Objective: Lipoprotein(a) [Lp(a)] is an atherogenic and prothrombotic lipoprotein associated with atherosclerotic cardiovascular disease (ASCVD). We assessed the association between regular aspirin use and ASCVD mortality among individuals with versus without elevated Lp(a) in a nationally representative US cohort. Methods: Eligible participants were aged 40–70 years without clinical ASCVD, reported on aspirin use, and had Lp(a) measurements from the Third National Health and Nutrition Examination Survey (NHANES III, 1988–1994), the only cycle of this nationally representative US cohort to measure Lp(a). Regular aspirin use was defined as taking aspirin ≥30 times in the previous month. Using NHANES III linked mortality records and weighted Cox proportional hazards regression, the association between regular aspirin use and ASCVD mortality was observed in those with and without elevated Lp(a) (≥50 versus |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2666-6677 |
Relation: | http://www.sciencedirect.com/science/article/pii/S2666667724000424; https://doaj.org/toc/2666-6677 |
DOI: | 10.1016/j.ajpc.2024.100674 |
URL الوصول: | https://doaj.org/article/397d51a3f8954de6bb2d5475f7fe1bf8 |
رقم الانضمام: | edsdoj.397d51a3f8954de6bb2d5475f7fe1bf8 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 26666677 |
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DOI: | 10.1016/j.ajpc.2024.100674 |