التفاصيل البيبلوغرافية
| العنوان: |
Association between HIV infection and hypertension: a global systematic review and meta-analysis of cross-sectional studies |
| المؤلفون: |
Katherine Davis, Pablo Perez-Guzman, Annika Hoyer, Ralph Brinks, Edward Gregg, Keri N. Althoff, Amy C. Justice, Peter Reiss, Simon Gregson, Mikaela Smit |
| المصدر: |
BMC Medicine, Vol 19, Iss 1, Pp 1-16 (2021) |
| بيانات النشر: |
BMC, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Medicine |
| مصطلحات موضوعية: |
HIV, Hypertension, Blood pressure, Systematic review, Meta-analysis, Medicine |
| الوصف: |
Abstract Background Improved access to effective antiretroviral therapy has meant that people living with HIV (PLHIV) are surviving to older ages. However, PLHIV may be ageing differently to HIV-negative individuals, with dissimilar burdens of non-communicable diseases, such as hypertension. While some observational studies have reported a higher risk of prevalent hypertension among PLHIV compared to HIV-negative individuals, others have found a reduced burden. To clarify the relationship between HIV and hypertension, we identified observational studies and pooled their results to assess whether there is a difference in hypertension risk by HIV status. Methods We performed a global systematic review and meta-analysis of published cross-sectional studies that examined hypertension risk by HIV status among adults aged > 15 (PROSPERO: CRD42019151359). We searched MEDLINE, EMBASE, Global Health and Cochrane CENTRAL to August 23, 2020, and checked reference lists of included articles. Our main outcome was the risk ratio for prevalent hypertension in PLHIV compared to HIV-negative individuals. Summary estimates were pooled with a random effects model and meta-regression explored whether any difference was associated with study-level factors. Results Of 21,527 identified studies, 59 were eligible (11,101,581 participants). Crude global hypertension risk was lower among PLHIV than HIV-negative individuals (risk ratio 0.90, 95% CI 0.85–0.96), although heterogeneity between studies was high (I 2 = 97%, p |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1741-7015 |
| Relation: |
https://doaj.org/toc/1741-7015 |
| DOI: |
10.1186/s12916-021-01978-7 |
| URL الوصول: |
https://doaj.org/article/391da01235be4936b8f3001571a3ca44 |
| رقم الانضمام: |
edsdoj.391da01235be4936b8f3001571a3ca44 |
| قاعدة البيانات: |
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