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Advances of Targeted Therapy Based on Estrogen Receptor Signaling Pathway in Lung Cancer

التفاصيل البيبلوغرافية
العنوان: Advances of Targeted Therapy Based on Estrogen Receptor Signaling Pathway in Lung Cancer
المؤلفون: Liqiang XU, Yongde LIAO, Hexiao TANG, Chao ZHANG, Zhaoguo LIU
المصدر: Chinese Journal of Lung Cancer, Vol 14, Iss 9, Pp 727-732 (2011)
بيانات النشر: Chinese Anti-Cancer Association; Chinese Antituberculosis Association, 2011.
سنة النشر: 2011
المجموعة: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
مصطلحات موضوعية: Estrogen receptor, Lung neoplasms, Targeted therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: Increasing evidence indicates that estrogen promotes tumor growth in both estrogen target organs and non-target organs. Estrogen regulates cell proliferation and differentiation via two different receptors, estrogen receptors α and β (ERα and ERβ). In recent decades, with the clarification of the ERα-mediated signaling pathways in breast cancer, targeted therapy through these pathways have successfully been used in clinical application. Tamoxifen, the classic representative, is a selective estrogen receptor modulator (SERM). Along with the elucidation of the role of estrogen in the pathophysiology of lung cancer, targeted lung cancer treatment based on the ER signaling pathways is also gradually being applied and it could become an important part of the comprehensive treatment for lung cancer.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: Chinese
تدمد: 1009-3419
1999-6187
Relation: https://doaj.org/toc/1009-3419; https://doaj.org/toc/1999-6187
DOI: 10.3779/j.issn.1009-3419.2011.09.07
URL الوصول: https://doaj.org/article/a37e990b6cd645f2b301e77a1066a655
رقم الانضمام: edsdoj.37e990b6cd645f2b301e77a1066a655
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:10093419
19996187
DOI:10.3779/j.issn.1009-3419.2011.09.07