Academic Journal
Topical timolol for superficial cutaneous infantile hemangiomas in very preterm infants
| العنوان: | Topical timolol for superficial cutaneous infantile hemangiomas in very preterm infants |
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| المؤلفون: | Matić Aleksandra, Prćić Sonja, Matić Milan |
| المصدر: | Vojnosanitetski Pregled, Vol 78, Iss 6, Pp 659-665 (2021) |
| بيانات النشر: | Military Health Department, Ministry of Defance, Serbia, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine (General) |
| مصطلحات موضوعية: | hemangioma, skin neoplasms, timolol, administration, topical, child, infant, premature, treatment, outcome, Medicine (General), R5-920 |
| الوصف: | Introduction. Infantile hemangiomas (IHs) occur 3 to 4 times more frequently in preterm infants than in those born at term. Yet, data about efficacy and safety of topical therapy for IHs in preterm infants, especially in those born with very low gestational age (less than 33 gestational weeks) is very scarce. Case report. We reported five very preterm girls treated with topical timolol maleate 0.5% gel for superficial cutaneous IHs. In four infants topical timolol was applied on a single IH each, and in one infant two IHs were treated. Out of six treated IHs, one was located on the face, four on the trunk and one on the leg. They were regularly monitored for IH involution and potential adverse effects of timolol for 6–13 months of local treatment. Good therapeutic effect was achieved in all the presented infants, with no adverse effects related to topical administration of timolol-maleate. Conclusion. Topical timolol is an effective and safe therapy for superficial cutaneous infantile hemangiomas in very preterm infants. The treatment should be discussed in detail with parents and individualized management plan should be tailored for each infant in order to maximize the chances of a successful outcome, while avoiding adverse effects. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Serbian |
| تدمد: | 0042-8450 2406-0720 |
| Relation: | https://doaj.org/toc/0042-8450; https://doaj.org/toc/2406-0720 |
| DOI: | 10.2298/VSP190219112M |
| URL الوصول: | https://doaj.org/article/37e22f47967d4e3b99f08e1b619c369b |
| رقم الانضمام: | edsdoj.37e22f47967d4e3b99f08e1b619c369b |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 00428450 24060720 |
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| DOI: | 10.2298/VSP190219112M |