Academic Journal
Baseline global longitudinal strain predictive of anthracycline-induced cardiotoxicity
| العنوان: | Baseline global longitudinal strain predictive of anthracycline-induced cardiotoxicity |
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| المؤلفون: | Raquel Araujo-Gutierrez, Kalyan R. Chitturi, Jiaqiong Xu, Yuanchen Wang, Elizabeth Kinder, Alpana Senapati, L. Bindu Chebrolu, Mahwash Kassi, Barry H. Trachtenberg |
| المصدر: | Cardio-Oncology, Vol 7, Iss 1, Pp 1-8 (2021) |
| بيانات النشر: | BMC, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | Global longitudinal strain, echocardiography, speckle tracking, anthracycline, cardiomyopathy, Diseases of the circulatory (Cardiovascular) system, RC666-701, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Abstract Background Cancer therapy-related cardiac dysfunction (CTRD) is a major source of morbidity and mortality in long-term cancer survivors. Decreased GLS predicts decreased left ventricular ejection fraction (LVEF) in patients receiving anthracyclines, but knowledge regarding the clinical utility of baseline GLS in patients at low-risk of (CTRD) is limited. Objectives The purpose of this study was to investigate whether baseline echocardiographic assessment of global longitudinal strain (GLS) before treatment with anthracyclines is predictive of (CTRD) in a broad cohort of patients with normal baseline LVEF. Methods Study participants comprised 188 patients at a single institution who underwent baseline 2-dimensional (2D) speckle-tracking echocardiography before treatment with anthracyclines and at least one follow-up echocardiogram 3 months after chemotherapy initiation. Patients with a baseline LVEF 10% from baseline and an overall reduced LVEF |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2057-3804 |
| Relation: | https://doaj.org/toc/2057-3804 |
| DOI: | 10.1186/s40959-021-00090-2 |
| URL الوصول: | https://doaj.org/article/37ad1fb0016e48c1b6031ed9b586225d |
| رقم الانضمام: | edsdoj.37ad1fb0016e48c1b6031ed9b586225d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20573804 |
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| DOI: | 10.1186/s40959-021-00090-2 |