Academic Journal
Correlation Between SNOT-22, Nasal Cytology, and Mood Disorders in Patients With Allergic Rhinitis Treated With a Liposomal Nasal Spray
| العنوان: | Correlation Between SNOT-22, Nasal Cytology, and Mood Disorders in Patients With Allergic Rhinitis Treated With a Liposomal Nasal Spray |
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| المؤلفون: | Maria Lauriello MD, Vittoria Di Rubbo MD, Gaia Sinatti MD, Marina Pasqua MD, Cinzia Tucci MD, Gian-Piero di Marco MD, Stefano Necozione MD, Alberto Eibenstein MD |
| المصدر: | Allergy & Rhinology, Vol 10 (2019) |
| بيانات النشر: | SAGE Publishing, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Otorhinolaryngology LCC:Immunologic diseases. Allergy |
| مصطلحات موضوعية: | Otorhinolaryngology, RF1-547, Immunologic diseases. Allergy, RC581-607 |
| الوصف: | Patients with allergic rhinitis (AR) can suffer from mood disorders. The aim of this study was to investigate the clinical effect of a liposomal nasal spray (LN) containing vitamins A and E on the nasal mucosa in patients suffering from AR who had refused any type of anti-allergic treatment. For this purpose, the results of nasal cytology, Visual Analog Scale (VAS), Sino-Nasal Outcome Test-22 (SNOT-22), and Hospital Anxiety and Depression Scale (HADS) test were analyzed. Moreover, we evaluated the relationship between SNOT-22 and nasal cytology and between nasal symptoms and HADS scores. Statistical analysis revealed a significant decrease of scores at T1 in the LN treatment group as concerns VAS, SNOT-22, HADS-Anxiety test and a remarkable reduction of inflammatory cells detected with nasal cytology. Our study showed that higher levels of SNOT-22 corresponded to a higher level of HADS-Anxiety. The mechanisms underlying this relationship in AR patients are currently unknown, but we can suppose that improving mucosal trophism may contribute to the decrease of nasal symptoms and anxiety scores. The improvement of nasal symptoms, as measured by SNOT-22, was significantly correlated with the objective results of nasal cytology. These relationships between SNOT-22 and nasal cytology and between anxiety and cytology were investigated for the first time in our research. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2152-6567 21526567 |
| Relation: | https://doaj.org/toc/2152-6567 |
| DOI: | 10.1177/2152656719866809 |
| URL الوصول: | https://doaj.org/article/366e89bf051549139cd01b61f6279abf |
| رقم الانضمام: | edsdoj.366e89bf051549139cd01b61f6279abf |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 21526567 |
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| DOI: | 10.1177/2152656719866809 |