Academic Journal
Adipokines and their Relation to Endothelial Dysfunction in Patients with Chronic Kidney Disease
| العنوان: | Adipokines and their Relation to Endothelial Dysfunction in Patients with Chronic Kidney Disease |
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| المؤلفون: | Madhusudan Ambarkar, Srinivasarao V.L.N. Pemmaraju, Sivakrishna Gouroju, Suchitra M Manohar, Aparna R Bitla, Naresh Yajamanam, Sivakumar Vishnubhotla |
| المصدر: | Journal of Clinical and Diagnostic Research, Vol 10, Iss 1, Pp BC04-BC08 (2016) |
| بيانات النشر: | JCDR Research and Publications Private Limited, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | adiponectin, cardiovascular disease, inflammation, interleukin, leptin, tumour necrosis factor-α, Medicine |
| الوصف: | Introduction: Chronic Kidney Disease (CKD) patients are at high risk of cardiovascular diseases (CVDs). Reduced nitric oxide (NO) bioavailability is a key element in connecting kidney disease to endothelial dysfunction (ED) and cardiovascular (CV) complications. Further, inflammation is implicated in ED in CKD. Besides these, adipose tissue factors were thought to have a role in inflammation and ED in CKD. Aim: It is proposed to evaluate the concentration changes of adipokines, inflammatory and ED markers in CKD patients compared to healthy controls. Further, to assess the associations between adipokines, inflammation and ED in CKD patients. Materials and Methods: A total of 120 CKD patients were included and classified into 3 groups based on Glomerular filtration rate (GFR). Group I (n=40) patients had a GFR between 60-119 ml/ min/1.73m2 (stage I, II), group II (n=40) had 15-59 ml/min/1.73m2 (stage III, IV) and group III (n=40) had |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2249-782X 0973-709X |
| Relation: | https://jcdr.net/articles/PDF/7060/15867_CE(RA1)_F(T)_PF1(Vsu_Om)_PFA(AK)_PF2(PAG).pdf; https://doaj.org/toc/2249-782X; https://doaj.org/toc/0973-709X |
| DOI: | 10.7860/JCDR/2016/15867.7060 |
| URL الوصول: | https://doaj.org/article/35fdc38353a34f258dd06f3b608951fa |
| رقم الانضمام: | edsdoj.35fdc38353a34f258dd06f3b608951fa |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2249782X 0973709X |
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| DOI: | 10.7860/JCDR/2016/15867.7060 |