Academic Journal

Association of Preablation Plasma Corin Levels With Atrial Fibrillation Recurrence After Catheter Ablation: A Prospective Observational Study

التفاصيل البيبلوغرافية
العنوان: Association of Preablation Plasma Corin Levels With Atrial Fibrillation Recurrence After Catheter Ablation: A Prospective Observational Study
المؤلفون: Yichang Zhao, Xiaoyang Yuan, Yunpeng Xie, Xiaomeng Yin, Ying Liu, Yuanjun Sun, Yue Gong, Jinqiu Liu, Feifei Chen
المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 2 (2024)
بيانات النشر: Wiley, 2024.
سنة النشر: 2024
المجموعة: LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: atrial fibrillation, catheter ablation, corin, natriuretic peptides, recurrence, Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Background We assessed the impact of pre‐ and postprocedural plasma corin levels on the recurrence of atrial fibrillation (AF) after catheter ablation (CA). Methods and Results This prospective, single‐center, observational study included patients undergoing their first CA of AF. Corin was measured before and 1 day after CA. The primary end point was recurrent AF between 3 and 12 months after ablation. From April 2019 through May 2021, we analyzed 616 patients with AF (59.09% men) with a mean age of 62.86±9.42 years. Overall, 153 patients (24.84%) experienced recurrent AF. In the recurrence group, the pre‐ and postprocedure corin concentrations were 539.14 (329.24–702.08) and 607.37 (364.50–753.80) pg/mL, respectively, which were significantly higher than the nonrecurrence group's respective concentrations of 369.05 (186.36–489.28) and 489.12 (315.66–629.05) pg/mL (both P494.85 pg/mL predicted AF recurrence at 1 year. An increase of 1 SD in corin concentrations before CA (264.94 pg/mL) increased the risk of recurrent AF by 54.3% after adjusting for confounding variables (hazard ratio, 1.465 [95% CI, 1.282–1.655]; P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2047-9980
Relation: https://doaj.org/toc/2047-9980
DOI: 10.1161/JAHA.123.031928
URL الوصول: https://doaj.org/article/35eccc85330e4ea2a89fabaa8bae6943
رقم الانضمام: edsdoj.35eccc85330e4ea2a89fabaa8bae6943
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20479980
DOI:10.1161/JAHA.123.031928