التفاصيل البيبلوغرافية
العنوان: |
Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia |
المؤلفون: |
Satoru Koyanagi, Naoki Kusunose, Marie Taniguchi, Takahiro Akamine, Yuki Kanado, Yui Ozono, Takahiro Masuda, Yuta Kohro, Naoya Matsunaga, Makoto Tsuda, Michael W. Salter, Kazuhide Inoue, Shigehiro Ohdo |
المصدر: |
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
بيانات النشر: |
Nature Portfolio, 2016. |
سنة النشر: |
2016 |
المجموعة: |
LCC:Science |
مصطلحات موضوعية: |
Science |
الوصف: |
Neuropathic pain hypersensitivity is known to undergo diurnal variations, although the underlying mechanisms are not clear. Using a sciatic nerve-injury mouse model, the authors find such diurnal changes are mediated by glucocorticoid induced enhancement of ATP release from astrocytes via pannexin-1 hemichannels. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/ncomms13102 |
URL الوصول: |
https://doaj.org/article/3429b7f186f44d12bff9bb7521dc6cb3 |
رقم الانضمام: |
edsdoj.3429b7f186f44d12bff9bb7521dc6cb3 |
قاعدة البيانات: |
Directory of Open Access Journals |