Academic Journal

Hypoallergen Peanut Lines Identified Through Large-Scale Phenotyping of Global Diversity Panel: Providing Hope Toward Addressing One of the Major Global Food Safety Concerns

التفاصيل البيبلوغرافية
العنوان: Hypoallergen Peanut Lines Identified Through Large-Scale Phenotyping of Global Diversity Panel: Providing Hope Toward Addressing One of the Major Global Food Safety Concerns
المؤلفون: Arun K. Pandey, Hari K. Sudini, Hari D. Upadhyaya, Rajeev K. Varshney, Manish K. Pandey
المصدر: Frontiers in Genetics, Vol 10 (2019)
بيانات النشر: Frontiers Media S.A., 2019.
سنة النشر: 2019
المجموعة: LCC:Genetics
مصطلحات موضوعية: reference set, peanut allergens, Ara h 1, Ara h 2, Ara h 3, Ara h 6, Genetics, QH426-470
الوصف: Peanut allergy is one of the serious health concern and affects more than 1% of the world’s population mainly in Americas, Australia, and Europe. Peanut allergy is sometimes life-threatening and adversely affect the life quality of allergic individuals and their families. Consumption of hypoallergen peanuts is the best solution, however, not much effort has been made in this direction for identifying or developing hypoallergen peanut varieties. A highly diverse peanut germplasm panel was phenotyped using a recently developed monoclonal antibody-based ELISA protocol to quantify five major allergens. Results revealed a wide phenotypic variation for all the five allergens studied i.e., Ara h 1 (4–36,833 µg/g), Ara h 2 (41–77,041 µg/g), Ara h 3 (22–106,765 µg/g), Ara h 6 (829–103,892 µg/g), and Ara h 8 (0.01–70.12 µg/g). The hypoallergen peanut genotypes with low levels of allergen proteins for Ara h 1 (4 µg/g), Ara h 2 (41 µg/g), Ara h 3 (22 µg/g), Ara h 6 (829 µg/g), and Ara h 8 (0.01 µg/g) have paved the way for their use in breeding and genomics studies. In addition, these hypoallergen peanut genotypes are available for use in cultivation and industry, thus opened up new vistas for fighting against peanut allergy problem across the world.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1664-8021
Relation: https://www.frontiersin.org/article/10.3389/fgene.2019.01177/full; https://doaj.org/toc/1664-8021
DOI: 10.3389/fgene.2019.01177
URL الوصول: https://doaj.org/article/337f041db3cc48e4ad8b326e42cec5b9
رقم الانضمام: edsdoj.337f041db3cc48e4ad8b326e42cec5b9
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16648021
DOI:10.3389/fgene.2019.01177