Academic Journal
Potency of nano-zinc oxide on caspase-3 of male quail exposed to lipopolysaccharide
| العنوان: | Potency of nano-zinc oxide on caspase-3 of male quail exposed to lipopolysaccharide |
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| المؤلفون: | Hiyam N. Maty, Hadeel M. Hameed, Ashwaq A. Hassan |
| المصدر: | Iraqi Journal of Veterinary Sciences, Vol 38, Iss 1, Pp 163-171 (2024) |
| بيانات النشر: | University of Mosul, College of Veterinary Medicine, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Veterinary medicine |
| مصطلحات موضوعية: | apoptosis, johnsen's score, testosterone, spermatogenesis, Veterinary medicine, SF600-1100 |
| الوصف: | It is known that lipopolysaccharide-induced endotoxemia promotes male sterility. This research project intended to examine the repercussions of nano-zinc oxide on caspase-3 and sex competence in male quail lipopolysaccharide-exposed cells. The quail were distributed at randomization into four groups; the first collection of birds was allowed to receive the usual feed and was used as a control, while the second collection was injected intraperitoneally LPS twice weekly at a prescribed dosage of 1 mg/kg body weight, the third collection was given nano-zinc oxide at a prescribed dosage of 40 mg/kg fodder for six weeks. The four-group collection was treated with the same nano zinc oxide particle dose and injected LPS at the same decided dose. The result indicates that management of the LPS effect significantly drops in testosterone, live sperm, sperm count, testis morphometric, and Johnsen's scoring, accompanied by a rise in dead, abnormal sperm and caspase-3 as linked with control. The application of NZO 40 mg/kg diet exhibited a higher significance in testosterone and live sperm with testicular criteria and Johnsen's scoring with drop dead, abnormal sperms, and caspase-3. Treated with nano-zinc oxide concurrently with LPS causes a rise in testosterone and Johnsen's scoring with a decrease in caspase-3 comparable to the LPS group and returns the value of testosterone hormone to normal value. It concluded that supplementation of nano zinc oxide is necessary to overcome the contamination with LPS, which negatively affects male sex characteristics, and nano zinc repairs that effect. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Arabic English |
| تدمد: | 1607-3894 2071-1255 |
| Relation: | https://www.vetmedmosul.com/article_181546_8266a62c821608cba6d8ec1b02fbb37e.pdf; https://doaj.org/toc/1607-3894; https://doaj.org/toc/2071-1255 |
| DOI: | 10.33899/ijvs.2023.141585.3121 |
| URL الوصول: | https://doaj.org/article/33285590c7084a7ca75718c8083eb940 |
| رقم الانضمام: | edsdoj.33285590c7084a7ca75718c8083eb940 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 16073894 20711255 |
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| DOI: | 10.33899/ijvs.2023.141585.3121 |