Academic Journal
Clinical profile, diagnostic challenges, and outcomes in subacute/chronic cerebral sinus venous thrombosis
| العنوان: | Clinical profile, diagnostic challenges, and outcomes in subacute/chronic cerebral sinus venous thrombosis |
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| المؤلفون: | Virender Sachdeva, Rohan Nalawade, Mohan Kannam, Rajat Kapoor, Goura Chattannavar, Sheetal Bajirao Kale, Jenil Sheth, Akshay Badakere, Debasmita Majhi, Vivekanand Uttamrao Warkad, Pratik Chougule, Ramesh Kekunnaya |
| المصدر: | Indian Journal of Ophthalmology, Vol 69, Iss 12, Pp 3598-3606 (2021) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Ophthalmology |
| مصطلحات موضوعية: | cerebral sinus venous thrombosis, chronic, diagnostic challenges, outcomes subacute, Ophthalmology, RE1-994 |
| الوصف: | Purpose: To report clinical profile, diagnostic challenges, and outcomes in cases of subacute/chronic cerebral sinus venous thrombosis (CSVT) presenting to neuro-ophthalmologists/neurologists. Methods: This was a multicentric, retrospective, observational study. Records of patients with neuroimaging proven subacute/chronic CSVT seen the from January 1, 2016 to March 31, 2020 were analyzed. Data collected included duration of symptoms, diagnosing physician, ophthalmological vs. focal/generalized neurological symptoms, optic disc examination, perimetry, and neuroimaging findings. Statistical analysis was performed using STATA software. Results: Forty-three patients with subacute (30)/chronic (13) CSVT were identified (32 males, 11 females). Median age was 37 (IQR 27–47) years. The presenting complaints were blurred vision 34 (79%), headaches in 25 (58%), vomiting 12 (28%), and diplopia 11 (26%). Eleven patients had associated sixth cranial nerve palsy. All but two patients had either disc edema/optic atrophy; four had unilateral disc edema at presentation. Ophthalmologists and neurologists diagnosed/suspected CSVT correctly in 13/29 (45%) and 11/14 (78.5%) patients, respectively. Most common initial alternate diagnosis was idiopathic intracranial hypertension in 12 (28%). Female gender, age ≤36, unilateral papilledema, not obtaining venogram at initial workup increased chances of initial alternate diagnosis. Median follow-up duration was 21 days. Average visual function remained stable in majority of patients at last follow-up. In total, 47.6% of patients had best-corrected visual acuity ≥20/30 at the final follow-up. Conclusion: In our series, subacute or chronic CSVT presented presented primarily with symptoms of intracranial hypertension. Unilateral papilledema, middle-aged patients, female gender, lack of focal/generalized neurological symptoms created diagnostic dilemma. Visual function remained stable in majority of patients. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0301-4738 1998-3689 |
| Relation: | http://www.ijo.in/article.asp?issn=0301-4738;year=2021;volume=69;issue=12;spage=3598;epage=3606;aulast=Sachdeva; https://doaj.org/toc/0301-4738; https://doaj.org/toc/1998-3689 |
| DOI: | 10.4103/ijo.IJO_96_21 |
| URL الوصول: | https://doaj.org/article/316b5d97499e46baab3f9bcc82637171 |
| رقم الانضمام: | edsdoj.316b5d97499e46baab3f9bcc82637171 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 03014738 19983689 |
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| DOI: | 10.4103/ijo.IJO_96_21 |